09q1

Targeting Trends Newsletter 09q1

Below are links to view the quarterly newsletter Targeting Trends. If you would like to be added to the mailing list, please complete the information on our contact page. Newsletter Highlights 2008 SfN Poster Award Winner (page 2) 2008 SfN Poster Award Runners Up (page 2) Teaser Winners (page 5) Tumor Cell Line Screening (page 7) …

Targeting Trends Newsletter 09q1 Read More »

Targeting Talk: Anti-IgM-ZAP

We were wondering how an IgM primary antibody might work in a Mab-ZAP assay. I realize that the conjugated antibody is an anti-IgG whole molecule antibody. However there may well be aspects/epitopes shared in common between IgG and IgM that might render an IgM primary useful with the Mab-ZAP reagent… or not? Has anyone looked …

Targeting Talk: Anti-IgM-ZAP Read More »

Targeting Topics 09q1

Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors Zhang W, Gardell S, Zhang D, Xie JY, Agnes RS, Badghisi H, Hruby VJ, Rance N, Ossipov MH, Vanderah TW, Porreca F, Lai J Brain 132(3):778-787, 2009. It has been hypothesized that a subset of rostral ventromedial medulla (RVM) neurons co-expressing the cholecystokinin …

Targeting Topics 09q1 Read More »

Cover Article: Selective deletion of CD8+ T cells by saporin-coupled MHC class I tetramers

Contributed by Paul R. Hess, Adam S. Buntzman, Sabrina L. Murray, Ellen F. Young, and Jeffrey A. Frelinger;North Carolina State University College of Veterinary Medicine, Raleigh, NC;and University of North Carolina-Chapel Hill School of Medicine, Chapel Hill, NC CD8+ T cells constitute important effectors of the adaptive immune response, functioning principally to remove infected cells …

Cover Article: Selective deletion of CD8+ T cells by saporin-coupled MHC class I tetramers Read More »