Anti-M-ZAP [IT-30, KIT-30]

a tool to “piggyback” onto YOUR antibody via affinity-purified goat anti-mouse IgM; targeting cells that recognize YOUR primary mouse monoclonal IgM antibody, eliminated via saporin

SKU: IT-30 Category: Antibody Type: affinity-purified | Host: Goat | Reactivity: Mouse | Conjugate: saporin | Usage: eliminates cells, screen antibodies |
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Anti-M-ZAP uses your primary mouse monoclonal IgM antibody to target and eliminate cells that recognize your primary antibody. The secondary conjugate uses the secondary antibody (affinity-purified goat anti-mouse IgM) to “piggyback” onto YOUR mouse primary antibody. Anti-M-ZAP can be utilized for screening mouse IgM antibodies for internalization and/or their suitability to make potent immunotoxins. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.

Anti-M-ZAP is a chemical conjugate of affinity-purified goat anti-mouse IgM and the ribosome-inactivating protein, saporin. It uses your primary mouse monoclonal IgM antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

Anti-M-ZAP is available individually (Cat. #IT-30) or as a kit (Cat. #KIT-30) which includes Anti-M-ZAPSaporin (Cat. #PR-01)Goat IgG-SAP (Cat. #IT-19) and reagents for developing a cytotoxicity assay.

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