CD25 Rat Monoclonal [AB-19]


SKU: AB-19 Category: Antibody Type: Monoclonal | Host: Rat | Reactivity: Mouse | Conjugate: unconjugated | Usage: flow cytometry, immunoprecipitation, proliferation inhibition, targeting agent |

Interleukin-2 receptors are located on the surface of T-cells and function in clonal expansion of the activated T-cell. The monoclonal CD-25 antibody inhibits the proliferation of Interleukin-2 (CD25)-dependent murine cell lines. It blocks the murine T-cell receptor for IL-2 by binding to the alpha-chain of IL-2 receptors. This antibody has also been shown to inhibit IL-2 binding to both low and high affinity IL-2 receptors.

This antibody recognizes the murine interleukin-2 (CD25) receptor. Cultured mouse B6.1 cytotoxic T-cells were used as immunogen. This antibody was produced in tissue culture supernatants.

Applications include proliferation inhibition, flow cytometry, immunoprecipitation, and targeting.

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