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custom-conjugates

Custom Saporin Conjugations

Q: We recently spoke to you about performing a custom saporin conjugation using our antibody. Is 0.09% azide in PBS...

Integrin α10-antibodies reduce glioblastoma tumor growth and cell migration

Masoumi KC, Huang X, Sime W, Mirkov A, Munksgaard Thorén M, Massoumi R, Lundgren-Åkerlund E (2021) Integrin α10-antibodies reduce glioblastoma...

Identification of prostaglandin F2 receptor negative regulator (PTGFRN) as an internalizable target in cancer cells for antibody-drug conjugate development

Marquez J, Dong J, Dong C, Tian C, Serrero G (2021) Identification of prostaglandin F2 receptor negative regulator (PTGFRN) as...

Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.

Knuplez E, Krier-Burris R, Cao Y, Marsche G, O’Sullivan J, Bochner BS (2020) Superior mouse eosinophil depletion in vivo targeting...

Labeling neuronal proteins with quantum dots for single-molecule imaging

Thal LB, Kovtun O, Rosenthal SJ (2020) Labeling neuronal proteins with quantum dots for single-molecule imaging. Methods Mol Biol 2135:169-177....

Cholinergic basal forebrain degeneration due to obstructive sleep apnoea increases Alzheimer’s pathology in mice.

Qian L, Kasas L, Milne MR, Rawashdeh O, Marks N, Sharma A, Bellingham MC, Coulson EJ (2020) Cholinergic basal forebrain...

Cell-specific ablation of GnRH neurons using kisspeptin-saporin in the preoptic area of sheep, but not mice.

Porter D, Moore A, Goodman R, Hileman S, Coolen L, Lehman M (2019) Cell-specific ablation of GnRH neurons using kisspeptin-saporin...

Integrin α10, a novel therapeutic target in glioblastoma, regulates cell migration, proliferation, and survival.

Thorén MM, Chmielarska Masoumi K, Krona C, Huang X, Kundu S, Schmidt L, Forsberg-Nilsson K, Floyd Keep M, Englund E,...

Novel high molecular weight albumin-conjugated angiotensin II activates β-arrestin and G-protein pathways.

Pang HW, Linares A, Couling L, Santollo J, Ancheta L, Daniels D, Speth RC (2019) Novel high molecular weight albumin-conjugated...

Evidence that the LH surge in ewes involves both neurokinin B-dependent and -independent actions of kisspeptin

Goodman RL, Lopez JA, Bedenbaugh MN, Connors JM, Hardy SL< Hileman SM, Coolen LM, Lehman MN (2018) Evidence that the...

Targeting of embryonic annexin A2 expressed on ovarian and breast cancer by the novel monoclonal antibody 2448

Cua S, Tan HL, Fong WJ, Chin A, Lau A, Ding V, Song Z, Yang Y, Choo A (2018) Targeting...

Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells.

O’Sullivan J, Carroll D, Cao Y, Salicru A, Bochner B (2018) Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and...

The cells and circuitry for itch responses in mice.

Mishra SK, Hoon MA (2013) The cells and circuitry for itch responses in mice. Science 340(6135):968-971. doi: 10.1126/science.1233765 Mishra SK,...

Do you remove unconjugated antibody from Custom Conjugates

Q: We are interested in having a custom conjugation of saporin and our antibody. Do you remove unconjugated antibody from...

Custom Mouse IgM Conjugate and Controls

Q: When we contacted you to find out more about having a custom saporin conjugation performed with our primary antibody,...