Souza G, Stornetta R, Stornetta D, Abbott S, Guyenet P (2019) Contribution of retrotrapezoid nucleus and carotid bodies to asphyxia‐induced arousal in rats. FASEB J 33(1):733.6. Experimental Biology 2019 Meeting Abstracts doi: 10.1096/fasebj.2019.33.1_supplement.733.6
Objective: To determine whether the retrotrapezoid nucleus (RTN) is implicated in CO2-induced arousal.
Summary: The authors confirm the importance of the CBs to hypoxia-induced arousal and demonstrate that arousal to hypercapnia is selectively reduced after RTN lesion.
Usage: RTN was nearly completely destroyed with microinjections of SSP-SAP (2.4 ng).
Related Products: SSP-SAP (Cat. #IT-11)