Janisiewicz AM, Jackson O, Firoz EF, Baxter MG (2004) Environment-spatial conditional learning in rats with selective lesions of medial septal cholinergic neurons. Hippocampus 14:265-273. doi: 10.1002/hipo.10175
Summary: 192-Saporin (Cat. #IT-01) has produced varied results when used to determine the role of cholinergic neurons of the medial septum/vertical limb of the diagonal band (MS/VDB) in spatial working memory. The authors used a total of 0.5 µl of 0.12 µg/µl 192-Saporin injected into the MS/VDB to examine “environment-spatial” conditional learning. The findings suggest that cholinergic neurons of the MS/VDB are involved in some aspects of conditional associative learning.
Related Products: 192-IgG-SAP (Cat. #IT-01)