Fargo KN, Sengelaub DR (2004) Testosterone manipulation protects motoneurons from dendritic atrophy after contralateral motoneuron depletion. J Comp Neurol 469(1):96-106. doi: 10.1002/cne.10991
Summary: The authors wished to investigate the therapeutic effects of testosterone on motoneuron dendrites in nerve injury models. 1 µl of a 0.1% solution of CTB-SAP (Cat. #IT-14) solution was unilaterally injected into the ispilateral bulbocavernosus and levator ani muscles of rats, and the contralateral motoneuron morphology was examined. In castrated rats receiving testosterone, dendrites in the spinal nucleus of the bulbocavernosus grew after CTB-SAP treatment. This is a demonstration of the neuroprotective/neurotherapeutic role of testosterone in the nervous system.
Related Products: CTB-SAP (Cat. #IT-14)