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A combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes.

A combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes.

Farhadi HF, Lepage P, Forghani R, Friedman HC, Orfali W, Jasmin L, Miller W, Hudson TJ, Peterson AC (2003) A combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes. J Neurosci 23(32):10214-10223. doi: 10.1523/JNEUROSCI.23-32-10214.2003

Summary: The authors used intrathecal injections of 0.3 µg CTB-SAP (Cat. #IT-14) to induce spinal cord demyelination for the purpose of defining the regulatory network controlling myelin basic protein transcription in mice.