Levita L, Mania I, Rainnie DG (2003) Subtypes of substance P receptor immunoreactive interneurons in the rat basolateral amygdala. Brain Res 981(1-2):41-51. doi: 10.1016/s0006-8993(03)02870-1
Summary: SP-SAP (Cat. #IT-07) has been used to lesion substance P receptor (SPr)-expressing neurons in the basolateral amygdala (BLA), but the interneuron subgroups targeted by SP-SAP in the BLA have not yet been defined. The authors used dual-labeling immunofluorescence to examine SPr colocalization with calbindin-D28K, parvalbumin, calretinin, somatostatin, and neuropeptide Y (NPY). All neurons in the BLA that express NPY also express the SPr and therefore SP-SAP, which specifically eliminates SP receptor-positive neurons is a useful tool to study the role of NPY in the BLA.
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