Chiken S, Tokuno H (2003) Ablation of striatal interneurons influences activities of entopeduncular neurons. Neuroreport 14(5):675-678. doi: 10.1097/00001756-200304150-00003
Summary: To investigate the role of the basal ganglia in informational processing of voluntary movement, the authors used SP-SAP (Cat. #IT-07) to lesion SP receptor-expressing neurons in the striatum. A 0.5 µl injection of 40 ng/µl SP-SAP into the dorsolateral portion of the striatum decreased the spontaneous discharge of entopeduncular neurons. These data indicate that SP receptor-positive striatal interneurons indirectly regulate activity of basal ganglia output neurons.
Related Products: SP-SAP (Cat. #IT-07)