Berchtold NC, Kesslak JP, Cotman CW (2002) Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. J Neurosci Res 68(5):511-521. doi: 10.1002/jnr.10256
Summary: Brain-derived neurotrophic factor (BDNF) enhances neuron function and plasticity. The authors lesioned rats with medial septal injections of 192-Saporin (Cat #IT-01, 375 ng in 0.5 µl PBS) or OX7-SAP (Cat #IT-02, 12.5 or 25 ng in 0.5 µl PBS). 192-Saporin affected the sedentary, but not exercise-induced levels of BDNF. OX7-SAP reduced levels in both groups in a dose-dependent manner.
Related Products: 192-IgG-SAP (Cat. #IT-01), OX7-SAP (Cat. #IT-02)