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Intervening B-type natriuretic peptide signaling for controlling chronic itch.

Meng J, Chen W, Wang J (2020) Intervening B-type natriuretic peptide signaling for controlling chronic itch. Brit J Pharmacol 177(5):1025-1040. doi: 10.1111/bph.14952

Objective: Review of recent findings used to examine the role of B-type natriuretic peptide (BNP) in itch transduction and the modulation of other pururitic proteins.

Summary: Mice treated with Nppb-SAP ablated 70% of the BNP receptor-positive neurons in the spinal cord.

Related Products: Nppb-SAP (Cat. #IT-69)

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