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  4. Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats.

Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats.

Kohli S, King MV, Williams S, Edwards A, Ballard TM, Steward LJ, Alberati D, Fone KCF (2019) Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats. Neuropsychopharmacology 44(2):295-305. doi: 10.1038/s41386-018-0171-0

Summary: The authors suggest that further evaluation such as by microinjection with selective antagonists or lesions using the neurotoxin, Oxytocin-SAP, would help delineate the brain region/s and receptor/s involved.

Related Products: Oxytocin-SAP (Cat. #IT-46)