Vogt LJ, Sim-Selley LJ, Childers SR, Wiley RG, Vogt BA (2001) Colocalization of mu-opioid receptors and activated G-proteins in rat cingulate cortex. J Pharmacol Exper Ther 299:840-848.
Summary: The anterior cingulate cortex (ACC) is a primary site of opiate drug action, and much of this activity is associated with the m-opioid receptor (MOR). The mechanisms by which MOR regulates pain in the ACC are not well understood. Using anti-DBH-SAP (7 µg into left lateral ventricle in rat; Cat. #IT-03) the authors mapped MOR activity in the ACC and evaluated the histochemical and behavioral relationships between MOR binding and mu-receptor-activated G-proteins after lesioning.
Related Products: Anti-DBH-SAP (Cat. #IT-03)