Keilholz A, Osman K, Smith C, Streeter K, Ozden I, Lever T, Nichols N (2024) Tongue exercise-induced plasticity in upper airway EMG activity in a model of hypoglossal motor neuron loss. Am Physiol Summit 39(S1) doi: 10.1152/physiol.2024.39.S1.1405
Objective: To study the impact of XII LMN degeneration and develop therapies to improve swallowing and breathing function/coordination.
Summary: The authors developed a novel rodent model of XII LMN loss using intralingual injections of CTB-SAP. Tongue exercise appears to enhance XII axis plasticity to improve upper airway function and coordination.
Usage: Intralingual injection of CTB-SAP (IT-14)
Related Products: CTB-SAP (Cat. #IT-14)