The gut-brain axis and cognitive control: A role for the vagus nerve

Décarie-Spain L, Hayes AMR, Lauer LT, Kanoski SE (2024) The gut-brain axis and cognitive control: A role for the vagus nerve. Semin Cell Dev Biol 156:201-209. doi: 10.1016/j.semcdb.2023.02.004 PMID: 36803834

Objective: To review evidence from rodent and human studies on how gastrointestinal vagus nerve signaling influences higher-order neurocognitive processes such as anxiety, motivation, learning, and memory.

Summary: The review highlights the integral role of gut-originating vagal pathways in regulating neurocognitive and affective functions, emphasizing their impact on adaptive behavioral responses and potential implications for neuropsychiatric disorders.

Usage: CCK-SAP (IT-31) was referenced in relation to prior studies involving gut vagal sensory ablation

Related Products: CCK-SAP (Cat. #IT-31)

See Also:

• Suarez AN et al. Gut vagal sensory signaling regulates hippocampus function through multi-order pathways. Nat Commun 9(1):2181, 2018.