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Regulation of memory function by feeding-relevant biological systems: Following the breadcrumbs to the hippocampus

Suarez AN, Noble EE, Kanoski SE (2019) Regulation of memory function by feeding-relevant biological systems: Following the breadcrumbs to the hippocampus. Front Mol Neurosci 12:101. doi: 10.3389/fnmol.2019.00101 PMID: 31057368

Objective: To review the literature describing interconnections between the memory and feeding circuits of the body.

Summary: Gastrointestinal and memory systems within the body are heavily intertwined, something that has been evolutionarily selected for by having to remember food locations, social factors, etc. CCK-SAP (IT-31) has been used to study the connection of gastrointestinal-derived vagal-sensory neurons by selectively lesioning them. These CCK-SAP-treated rats were compared to un-lesioned animals and showed reduced brain-derived neurotrophic factor and memory impairment

Related Products: CCK-SAP (Cat. #IT-31)

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