Sainz AE (2023) The effects of loss of orexin neurons on attention. William & Mary Thesis.
Objective: This paper examines the effects of loss of orexin neurons on attention in mice.
Summary: This undergraduate honors thesis from William & Mary tested attention in mice after selective loss of orexin neurons, which are important for arousal. The researchers found impairments in sustained attention and cognitive flexibility in the mice missing orexin neurons.
Usage: 0.5 µl of Orexin-B-SAP (0.4 µg/µl) or saline was administered to both sides of the lateral hypothalamus for 30 seconds using a 1 µl syringe.
Related Products: Orexin-B-SAP (Cat. #IT-20)