Sun S, Ding Z, Yang X, Zhao X, Zhao M, Gao L, Chen Q, Xie S, Liu A, Yin S, Xu Z, Lu X (2021) Nanobody: a small antibody with big implications for tumor therapeutic strategy. Int J Nanomedicine 16:2337-2356. doi: 10.2147/IJN.S297631
Summary: This Journal Club commentary focuses on the publication by Kalinchuk et al.
Usage: The author refers to work with 192-IgG-SAP published by Blanco-Centurion et al. This group investigated whether basal forebrain cholinergic neurons are involved in adenosine regulation of sleep. 6 µg of 192-IgG-SAP was administered to the lateral ventricle of rats.
Related Products: 192-IgG-SAP (Cat. #IT-01)
- Blanco-Centurion C et al. Adenosine and sleep homeostasis in the basal forebrain. J Neurosci 26(31):8092-8100, 2006.
- Kalinchuk AV et al. The role of cholinergic basal forebrain neurons in adenosine-mediated homeostatic control of sleep: lessons from 192 IgG-saporin lesions. Neuroscience 157:238-253, 2008.