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  4. Fluoxetine and ketamine reverse the depressive but not anxiety behavior induced by lesion of cholinergic neurons in the horizontal limb of the diagonal band of broca in male rat

Fluoxetine and ketamine reverse the depressive but not anxiety behavior induced by lesion of cholinergic neurons in the horizontal limb of the diagonal band of broca in male rat

Chen L, Ke Y, Ma H, Gao L, Zhou Y, Zhu H, Liu H, Zhang F, Zhou W (2021) Fluoxetine and ketamine reverse the depressive but not anxiety behavior induced by lesion of cholinergic neurons in the horizontal limb of the diagonal band of broca in male rat. Front Behav Neurosci 15:602708. doi: 10.3389/fnbeh.2021.602708

Summary: A lesion of horizontal limb of the diagonal band of Broca (HDB) cholinergic neurons and followed hippocampus damage may be involved in the pathogenesis of depression.

Usage: Injections of 192-IgG-SAP were made bilaterally into the HDB in a volume of 0.5 µL per side with a concentration of 0.5 µg/µL.

Related Products: 192-IgG-SAP (Cat. #IT-01)