Chew C, Sengelaub DR (2019) Neuroprotective effects of exercise on the morphology of somatic motoneurons following the death of neighboring motoneurons. Neurorehabil Neural Repair 33(8):656-667. doi: 10.1177/1545968319860485
Objective: To explore whether exercise shows the same neuroprotective effect on induced dendritic atrophy as that seen with androgen treatment.
Summary: Exercise following neural injury exerts a protective effect on motoneuron dendrites comparable to that seen with exogenous androgen treatment.
Usage: Motoneurons innervating the left vastus medialis muscle were selectively killed by intramuscular injection of CTB-SAP (2 μL, 0.1%). Saporin injection reduced the weight of the vastus medialis muscle; exercise had no effect on muscle weight.
Related Products: CTB-SAP (Cat. #IT-14)