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Depletion of C1 neurons attenuates the salt-induced hypertension in unanesthetized rats.

Ribeiro N, Martins Sá RW, Antunes VR (2020) Depletion of C1 neurons attenuates the salt-induced hypertension in unanesthetized rats. Brain Res 1748:147107. doi: 10.1016/j.brainres.2020.147107

Objective: To determine if the ablation of C1 neurons mitigates high blood pressure induced by high-salt intake.

Summary: Data show that hypertension induced by high-salt intake is dependent on C1 neurons.

Usage: Bilateral injections of 2.4 ng/100 nl of Anti-DBH-SAP. The total number of TH+ neurons in the AS region was reduced by 37 ± 13% in the anti-DBH-SAP group when compared to control.

Related Products: Anti-DBH-SAP (Cat. #IT-03)

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