Borkowski LF, Nichols NL (2019) A2A and 5‐HT receptors are differentially required for respiratory plasticity over the course of motor neuron loss in intrapleurally CTB-SAP treated rats. FASEB J 33(1):843.3. Experimental Biology 2019 Meeting Abstracts doi: 10.1096/fasebj.2019.33.1_supplement.843.3
Objective: To investigate the role of serotonin (5-HT) and adenosine 2A (A2A) receptors in respiratory plasticity.
Summary: A2A receptors are necessary for respiratory plasticity early (7d), but 5-HT receptors are required late (28d).
Usage: Bilateral, intrapleural injections of: 1) CTB-SAP (25 μg), or 2) un-conjugated CTB and SAP (control) in rats.
Related Products: CTB-SAP (Cat. #IT-14)