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  4. Oscillatory coupling within neonatal prefrontal-hippocampal networks is independent of selective removal of GABAergic neurons in the hippocampus.

Oscillatory coupling within neonatal prefrontal-hippocampal networks is independent of selective removal of GABAergic neurons in the hippocampus.

Bitzenhofer SH, Hanganu-Opatz IL (2014) Oscillatory coupling within neonatal prefrontal-hippocampal networks is independent of selective removal of GABAergic neurons in the hippocampus. Neuropharmacology 77:57-67. doi: 10.1016/j.neuropharm.2013.09.007

Summary: During cognitive tasks neuronal networks are entrained by oscillatory electrical rhythms with different frequencies. It has been proposed that GABAergic neurons in the prefrontal-hippocampal networks control this processing. The authors administered 252 ng of Anti-vGAT-SAP (Cat. #IT-71) into the ventral hippocampus of rats to examine how the GABAergic neurons could be involved. Unconjugated anti-vGAT (Cat #AB-N44) was used as a control. Hippocampal sharp waves were impaired during neonatal development, but the data indicate that oscillatory coupling between the neonatal prefrontal cortex and hippocampus is not controlled by GABAergic hippocampal interneurons.

Related Products: Anti-vGAT-SAP (Cat. #IT-71), vGAT Rabbit Polyclonal (Cat. #AB-N44)