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ALPPL2 is a highly specific and targetable tumor cell surface antigen

Su Y, Zhang X, Bidlingmaier S, Behrens CR, Lee NK, Liu B (2020) ALPPL2 is a highly specific and targetable tumor cell surface antigen. Cancer Res 80(20):4552-4564. doi: 10.1101/2020.01.07.898122

Objective: To evaluate therapeutic potential of ALPPL2 targeting.

Summary: Exquisite tissue specificity and broad tumor type coverage suggest that ALPPL2 could be an excellent cell surface target for therapeutic development against mesothelioma.

Usage: Biotinylated M25 IgG1 and Streptavidin-ZAP were mixed at a molar ratio of 1:1.

Related Products: Streptavidin-ZAP (Cat. #IT-27)