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  4. Effects of noradrenergic alpha-2 receptor antagonism or noradrenergic lesions in the ventral bed nucleus of the stria terminalis and medial preoptic area on maternal care in female rats.

Effects of noradrenergic alpha-2 receptor antagonism or noradrenergic lesions in the ventral bed nucleus of the stria terminalis and medial preoptic area on maternal care in female rats.

Smith CD, Holschbach MA, Olsewicz J, Lonstein JS (2012) Effects of noradrenergic alpha-2 receptor antagonism or noradrenergic lesions in the ventral bed nucleus of the stria terminalis and medial preoptic area on maternal care in female rats. Psychopharmacology (Berl) 224(2):263-276. doi: 10.1007/s00213-012-2749-2

Summary: The authors investigated the function of norepinephrine in mothering. Lesioned animals received 55-ng infusions of anti-DBH-SAP (Cat. #IT-03) into the ventral bed nucleus of the stria terminalis. Mouse-IgG-SAP (Cat. #IT-18) was used as a control. The results demonstrate that downregulated noradrenergic activity is necessary for postpartum maternal behavior, but is not enough to elicit maternal behavior in nulliparous females.

Related Products: Anti-DBH-SAP (Cat. #IT-03), Mouse IgG-SAP (Cat. #IT-18)

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