1. Home
  2. Knowledge Base
  3. References
  4. Activation of immobility-related hippocampal theta by cholinergic septohippocampal neurons during vestibular stimulation.

Activation of immobility-related hippocampal theta by cholinergic septohippocampal neurons during vestibular stimulation.

Tai SK, Ma J, Ossenkopp KP, Leung LS (2012) Activation of immobility-related hippocampal theta by cholinergic septohippocampal neurons during vestibular stimulation. Hippocampus 22(4):914-925 . doi: 10.1002/hipo.20955

Summary: The vestibular system is highly involved with spatial navigation and memory. It is thought that modulation of hippocampal function by the vestibular system is mediated by a hippocampal theta rhythm. Rats received 140 ng of 192-IgG-SAP (Cat. #IT-01) infused into the medial septum, followed by measurement of hippocampal EEG’s and evoked potentials. Theta was attenuated in rats receiving the lesion, as well as other changes that suggest the importance of septohippocampal cholinergic activity in sensorimotor processing and spatial memory.

Related Products: 192-IgG-SAP (Cat. #IT-01)