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  4. Septohippocampal pathways contribute to system consolidation of a spatial memory: Sequential implication of gabaergic and cholinergic neurons.

Septohippocampal pathways contribute to system consolidation of a spatial memory: Sequential implication of gabaergic and cholinergic neurons.

Lecourtier L, de Vasconcelos AP, Leroux E, Cosquer B, Geiger K, Lithfous S, Cassel JC (2011) Septohippocampal pathways contribute to system consolidation of a spatial memory: Sequential implication of gabaergic and cholinergic neurons. Hippocampus 21(12):1277-1289. doi: 10.1002/hipo.20837

Summary: Few studies have examined the role of GABAergic septohippocampal projections in memory consolidation. The authors administered 192-IgG-SAP (400 ng; Cat. #IT-01) and/or orexin-SAP (70 ng; Cat. #IT-20) to the medial septum/vertical limb of the diagonal band of Broca of rats. Spatial memory tests were then administered over several weeks. The data indicate that both GABAergic and cholinergic septohippocampal systems contribute to memory stabilization, possibly in a sequential manner.

Related Products: 192-IgG-SAP (Cat. #IT-01), Orexin-B-SAP (Cat. #IT-20)

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