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Gene regulation in the rat prefrontal cortex after learning with or without cholinergic insult.

Paban V, Chambon C, Farioli F, Alescio-Lautier B (2011) Gene regulation in the rat prefrontal cortex after learning with or without cholinergic insult. Neurobiol Learn Mem 95(4):441-452. doi: 10.1016/j.nlm.2011.02.005

Summary: Microarray technology was used to screen gene expression in a model of attention and memory deficit. Rats received bilateral injections of 192-IgG-SAP (Cat. #IT-01) into the medial septum and nucleus basalis magnocellularis (37.5 ng per side and 75 ng per side respectively). Gene expression in memory loss following the lesion was defined by one cluster related to cytoskeleton organization and proliferation, and glial and vascular remodeling. These are processes associated with brain repair after injury.

Related Products: 192-IgG-SAP (Cat. #IT-01)

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