Pongratz G, Melzer M, Straub R (2012) The sympathetic nervous system stimulates anti-inflammatory B cells in collagen-type II-induced arthritis. Ann Rheum Dis 71(3):432-9. doi: 10.1136/ard.2011.153056
Summary: The sympathetic nervous system exerts anti-inflammatory effects on collagen-induced arthritis. To examine whether these effects are mediated by B-cells producing interleukin-10 (IL-10) the authors treated mice with 5 µg intraperitoneal injections of anti-DBH-SAP (Cat. #IT-03). The sympathectomy efficacy was assessed by analyzing norepinephrine levels in the spleen. The data suggest that increasing the number of IL-10 producing B cells can slow down arthritis progression.
Related Products: Anti-DBH-SAP (Cat. #IT-03)