Chen AI, Nguyen CN, Copenhagen DR, Badurek S, Minichiello L, Ranscht B, Reichardt LF (2011) TrkB (Tropomyosin-related kinase B) controls the assembly and maintenance of GABAergic synapses in the cerebellar cortex. J Neurosci 31(8):2769-2780. doi: 10.1523/JNEUROSCI.4991-10.2011 PMID: 21414899
Summary: In this work the authors investigated the role of TrkB in GABAergic inhibitory synapses in the mouse cerebellar cortex. Using a variety of techniques, including immunohistochemistry utilizing an mGluR2 antibody (Cat. #AB-N32), it was shown that TrkB is required for both assembly and maintenance of these synapses. The primary role of TrkB appears to be regulating the localization of synaptic constituents.
Related Products: Metabotropic Glutamate Receptor 2 (mGluR2) Mouse Monoclonal (Cat. #AB-N32)