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  4. A common neuronal mechanism of hypertension and sleep disturbances in spontaneously hypertensive rats: Role of orexinergic neurons.

A common neuronal mechanism of hypertension and sleep disturbances in spontaneously hypertensive rats: Role of orexinergic neurons.

Cui S-Y, Huang Y-L, Cui X-Y, Zhao H-L, Hu X, Liu Y-T, Qin Y, Kurban N, Zhang Y-H (2020) A common neuronal mechanism of hypertension and sleep disturbances in spontaneously hypertensive rats: Role of orexinergic neurons. Prog Neuropsychopharmacol Biol Psychiatry 100:109902. doi: 10.1016/j.pnpbp.2020.109902

Objective: To investigate dynamic changes in sleep patterns during the development of hypertension.

Summary: Although the correlation between sleep disturbances and hypertension is very complex, common mechanisms may underlie these comorbidities.

Usage: Orexin-B-SAP (HCRT2-SAP) was administered in two injections/side (100 and 200 ng/0.5 μl/injection).

Related Products: Orexin-B-SAP (Cat. #IT-20)