Marshall AM, Nommsen-Rivers LA, Hernandez LL, Dewey KG, Chantry CJ, Gregerson KA, Horseman ND (2010) Serotonin transport and metabolism in the mammary gland modulates secretory activation and involution. J Clin Endocrinol Metab 95(2):837-846. doi: 10.1210/jc.2009-1575 PMID: 19965920
Summary: Serotonin is known to be a local regulator of lactation homeostasis. This work examined the roles of the serotonin reuptake transporter (SERT) and monoamine oxidase in this system. Immunohistochemical and immunocytochemical staining was done on human primary mammary epithelial cells and mouse tissue with an anti-SERT antibody (Cat. #AB-N09). Additional data included epidemiological studies and selective serotonin reuptake inhibitor treatment of mice. The results suggest that women taking SSRI inhibitor medications were more likely to experience delayed secretory activation.
Related Products: Antibody to Serotonin Transporter (SERT, Cat. #AB-N09)