Riedl MS, Braun PD, Kitto KF, Roiko SA, Anderson LB, Honda CN, Fairbanks CA, Vulchanova L (2009) Proteomic analysis uncovers novel actions of the neurosecretory protein VGF in nociceptive processing. J Neurosci 29:13377-13388. doi: 10.1523/JNEUROSCI.1127-09.2009
Summary: Peripheral tissue injury can alter protein expression in sensory neurons, which may contribute to abnormal nociceptive processing. The authors used cultured dorsal root ganglion neurons as a model for axotomized neurons to examine early changes in protein expression after nerve injury. Several different parameters were measured, including immunohistochemistry using anti-TrkA (Cat. #AB-N03). The data show an increased level of a putative neuropeptide precursor, VGF, as a result of nerve injury.
Related Products: trkA Rabbit Polyclonal (Cat. #AB-N03)