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Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors.

Barry DM, Liu XT, Liu B, Liu XY, Gao F, Zeng X, Liu J, Yang Q, Wilhelm S, Yin J, Tao A, Chen ZF (2020) Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors. Nat Commun 11(1):1397. doi: 10.1038/s41467-020-15230-y

Objective: To determine the role of GRP in sensory neurons.

Summary: GRP is a neuropeptide in sensory neurons for nonhistaminergic itch, and GRP sensory neurons are dedicated to itch transmission.

Usage: Bombesin-SAP (200 ng/5 μL, i.t.) was injected 2 weeks prior to optical stimulation.

Related Products: Bombesin-SAP (Cat. #IT-40)

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