Dotigny F, Ben Amor AY, Burke M, Vaucher E (2008) Neuromodulatory role of acetylcholine in visually-induced cortical activation: Behavioral and neuroanatomical correlates. Neuroscience 154(4):1607-1618. doi: 10.1016/j.neuroscience.2008.04.030
Summary: Acetylcholine is thought to have a neuromodulatory role in visual processing. After rats were treated with 192-IgG-SAP (Cat. #IT-01, 2 µl of 2.4 µg/µl into the lateral ventricle) visual acuity and performance in a visual water maze task were analyzed. Lesioned animals displayed no loss in acuity, but were less able to learn a new orientation discrimination task. These data suggest that the cholinergic system in the basal forebrain plays an important role in post-synaptic visual processing.
Related Products: 192-IgG-SAP (Cat. #IT-01)