Pascual J, Heinrichs SC (2007) Olfactory neophobia and seizure susceptibility phenotypes in an animal model of epilepsy are normalized by impairment of brain corticotropin releasing factor. Epilepsia 48:827-833. doi: 10.1111/j.1528-1167.2007.01024.x
Summary: Olfactory recognition has been linked to epilepsy in behavioral phenotype models. This work examines the role brain stress neuropeptides play in the manifestation of neurological perturbations. Mice were injected with 2 µg/5 µl of CRF-SAP (Cat. #IT-13) into the lateral ventricle. Saporin (Cat. #PR-01) was used as a control. The lesioned mice displayed a temporary reduction in seizure susceptibility, and the reversal of olfactory deficits towards the detection of food.
Related Products: CRF-SAP (Cat. #IT-13), Saporin (Cat. #PR-01)