Yu YQ, Barry DM, Hao Y, Liu XT, Chen ZF. (2017) Molecular and Neural Basis of Contagious Itch Behavior in Mice. Science 355(6329):1072-76. PMID: 28280205 Observing others scratch themselves can make you want to do so. This contagious itching has been observed in monkeys and humans, but what about rodents? Yu et al. found that […]
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Martínez-Gardeazabal J, González de San Román E, Moreno-Rodríguez M, Llorente-Ovejero A, Manuel I, Rodríguez-Puertas R. (2017) Lipid Mapping of the Rat Brain for Models of Disease. Biochim Biophys Acta PMID:28235468 The major components of plasma membranes are lipids. These molecules have a wide range of functions including cellular structure, metabolism and signaling molecules. Regarding this
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Somasundaram et al. C-terminal phosphorylation regulates the kinetics of a subset of melanopsin-mediated behaviors in mice. PNAS (2017), pii: 201611893. PMID: 28223508 Chronotype (morningness-eveningness) in mammals likely has multiple causes. Phase angle of entrainment is defined as the relationship between the timing of the biological clock and the timing of an external time cue, and if the primary
Melanopsin photoresponse relies on the SEE-terminus Read More »
Lecrux et al. Impact of altered cholinergic tones on the neurovascular coupling response to whisker stimulation. Journal of Neuroscience (2017), 1784-16. PMID: 28069927 Brain imaging techniques that use vascular signals to map changes in neuronal activity rely on the coupling between electrophysiology and hemodynamics, a phenomenon referred to “neurovascular coupling” (NVC). It is unknown whether
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Jiao et al. Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves. EBioMedicine (2016) 10:282-90. PMID: 27394642 Individuals with bicuspid aortic valves (BAV) are at a higher risk of developing thoracic aortic aneurysms (TAA) than patients with trileaflet aortic valves (TAV). Aneurysms associated with BAV most commonly
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Humana Press has released its newest offer to the Neuroscience community, Molecular Neurosurgery With Targeted Toxins, with Ronald G. Wiley and Douglas A. Lappi as editors. This book contains articles by “the best and the brightest” who have used targeted toxins for probing difficult in vivo systems biology issues. To order — please contact ATS
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Internalization Technology to eliminate specific cells Advanced Targeting Systems’ technology – Molecular Surgery – is a modification of one of the most widely used techniques in the neurosciences: lesioning of a region by surgical means and observation of the effect. Saporin has no way of entering a cell on its own, except by bulk-phase endocytosis.
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