Author name: Kristen Hartman

Targeted drug delivery using nanobodies to deliver effective molecules to breast cancer cells: The most attractive application of nanobodies

Abdolvahab MH, Karimi P, Mohajeri N, Abedini M, Zare H (2024) Targeted drug delivery using nanobodies to deliver effective molecules to breast cancer cells: The most attractive application of nanobodies. Cancer Cell Int 24(1):67. doi: 10.1186/s12935-024-03259-8 PMID: 38341580 Objective: Using nanobodies to deliver saporin to breast cancer cells. Summary: Through the binding of saporin to […]

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The effect of NK3-Saporin injection within the arcuate nucleus on puberty, the LH surge, and the response to Senktide in female sheep

Aerts EG, Griesgraber MJ, Shuping SL, Bowdridge EC, Hardy SL, Goodman RL, Nestor CC, Hileman SM (2024) The effect of NK3-Saporin injection within the arcuate nucleus on puberty, the LH surge, and the response to Senktide in female sheep. Biol Reprod 110(2):275-287. doi: 10.1093/biolre/ioad147 PMID: 37930247 Objective: To investigate the role of NKB-SAP (NK3-SAP) in

The effect of NK3-Saporin injection within the arcuate nucleus on puberty, the LH surge, and the response to Senktide in female sheep Read More »

Investigating the cytosolic delivery of proteins by lipid nanoparticles using the chloroalkane penetration assay

Wang J, Zhang S, Li Y, Xu Q, Kritzer JA (2024) Investigating the cytosolic delivery of proteins by lipid nanoparticles using the chloroalkane penetration assay. Biochemistry doi: 10.1021/acs.biochem.3c00614 PMID: 38334719 Objective: To investigate bovine serum albumin (BSA) protein encapsulation and release within polylysine/polyglutamate (PLys/PGlu) coacervates. Summary: The findings emphasize the importance of ingredient addition sequence

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Retinal response to systemic inflammation differs between sexes and neurons

Rodríguez-Ramírez KT, Norte-Muñoz M, Lucas-Ruiz F, Gallego-Ortega A, Calzaferri F, García-Bernal D, Martínez CM, Galindo-Romero C, de Los Ríos C, Vidal-Sanz M, Agudo-Barriuso M (2024) Retinal response to systemic inflammation differs between sexes and neurons. Front Immunol 15:1340013. doi: 10.3389/fimmu.2024.1340013 PMID: 38384465 Objective: To examine how systemic inflammation, induced by intraperitoneal administration of lipopolysaccharide (LPS),

Retinal response to systemic inflammation differs between sexes and neurons Read More »

Efficacy and specificity of melanopsin reporters for retinal ganglion cells

Maloney R, Quattrochi L, Yoon J, Souza R, Berson D (2024) Efficacy and specificity of melanopsin reporters for retinal ganglion cells. J Comp Neurol 532(2):e25591. doi: 10.1002/cne.25591 PMID: 38375612 Objective: To evaluate the precision and comprehensiveness of various labeling methods for intrinsically photosensitive retinal ganglion cells (ipRGCs). Summary: The authors provide a comparative analysis of

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Cell lipotypes localization in brain by mass spectrometry imaging

Martínez-Gardeazabal J, Moreno-Rodríguez M, Llorente-Ovejero A, González de San Román E, Lombardero L, Bengoetxea de Tena I, Sustacha J, Matute C (2024) Cell lipotypes localization in brain by mass spectrometry imaging. bioRxiv doi: 10.1101/2024.02.02.578599 Objective: Characterizing the type of different central nervous system cells via mass spectrometry of their component lipids. Summary: Different varieties of

Cell lipotypes localization in brain by mass spectrometry imaging Read More »

Cadherin-13 Maintains Retinotectal Synapses via Transneuronal Interactions

Matcham AC, Toma K, Tsai NY, Sze CJ, Lin PY, Stewart IF, Duan X (2024) Cadherin-13 Maintains Retinotectal Synapses via Transneuronal Interactions. J Neurosci 44(5):e1310232023. doi: 10.1523/JNEUROSCI.1310-23.2023 PMID: 38123991 Objective: To explore the role of Type II cadherins, particularly Cdh13, in the formation of specific retinotectal synapses. Summary: Cdh13 is highly expressed in wide-field neurons

Cadherin-13 Maintains Retinotectal Synapses via Transneuronal Interactions Read More »

The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson’s disease

Björklund A, Barker RA (2024) The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson’s disease. Brain awae026. doi: 10.1093/brain/awae026 PMID: 38279949 Objective: Review the use of cholinergic cell replacement as a potential therapeutic strategy in Parkinson’s Disease (PD) and how rodent models of PD-like cognitive decline can be used by analyzing

The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson’s disease Read More »

Chemical and biological characterization of vaccine adjuvant QS-21 produced via plant cell culture

Lv X, Martin J, Hoover H, Joshi B, Wilkens M, Ullisch DA, Leibold T, Juchum JS, Revadkar S, Kalinovska B, Keith J, Truby A, Liu G, Sun E, Haserick J, DeGnore J, Conolly J, Hill AVS, Baldoni J, Kensil C, Levey D, Spencer AJ, Gorr G, Findeis M, Tanne A (2024) Chemical and biological characterization

Chemical and biological characterization of vaccine adjuvant QS-21 produced via plant cell culture Read More »

Identification of a novel perifornical-hypothalamic-area-projecting serotonergic system that inhibits innate panic and conditioned fear responses

Bernabe CS, Caliman IF, de Abreu ARR, Molosh AI, Truitt WA, Shekhar A, Johnson PL (2024) Identification of a novel perifornical-hypothalamic-area-projecting serotonergic system that inhibits innate panic and conditioned fear responses. Transl Psychiatry 14(1):60. doi: 10.1038/s41398-024-02769-3 PMID: 38272876 Objective: To investigate the role of serotonergic inputs from the raphe nuclei to the perifornical hypothalamic area

Identification of a novel perifornical-hypothalamic-area-projecting serotonergic system that inhibits innate panic and conditioned fear responses Read More »

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