pHast Conjugates, Fast Tools
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Disease-Modeling Saporin Conjugates
Product Disease Model 192-IgG-SAP (Cat. #IT-01) Alzheimer’s Disease Acetylated LDL-SAP (Cat. #IT-08) Alzheimer’s Disease Anti-ChAT-SAP (Cat. #IT-42) Alzheimer’s Disease, Down syndrome, Rett syndrome Anti-DAT-SAP (Cat. #IT-25) Parkinson’s Disease Anti-DBH-SAP (Cat. #IT-03) Alzheimer’s Disease CTB-SAP (Cat. #IT-14) Lou Gehrig’s Disease (Amyotrophic lateral sclerosis, ALS) GAT1-SAP (Cat. #IT-32) Epilepsy Mac-1-SAP mouse/human (Cat. #IT-06) Alzheimer’s Disease ME20.4-SAP (Cat.
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Saporin as the Scalpel
Saporin as the Scalpel The Proxima recently hosted a 2-day joint conference on Dementia, Alzheimer’s and Parkinson’s diseases (DAPD-2025) and Neurodegenerative & Neuromuscular diseases (NND-2025). The hybrid conferences took place in the beautiful city of Barcelona, Spain and online during June 19-20, 2025. As authors of the publication, “Saporin as a Commercial Reagent: Its Uses
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Influence of neurokinin b, dynorphin a and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes
Szysiak N, Kosior-Korzecka U, longo V, Patkowski K, Greguła-Kania M, Nowakiewicz A, Bochniarz M,Junkuszew A (2025) Influence of neurokinin b, dynorphin a and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes. J Vet Res doi: 10.2478/jvetres-2025-0003 Objective: The aim of the study was to analyze the direct effect of
Targeted depletion of dysfunctional hematopoietic stem cells mitigates myeloid-biased differentiation in aged mice
Ren X, Wang Y, Zhang Y (2025) Targeted depletion of dysfunctional hematopoietic stem cells mitigates myeloid-biased differentiation in aged mice. Cell Discov 11:56. doi: 10.1038/s41421-025-00810-3 PMID: 40490480 Objective: To develop and evaluate a targeted strategy for depleting dysfunctional, myeloid-biased CD150-high hematopoietic stem cells (HSCs) in aged mice to restore balanced hematopoiesis and mitigate aging-related blood
Saporin Conjugates
Targeted SAP conjugates are powerful and specific lesioning agents used in the technique known as Molecular Surgery ZAP conjugates are non-targeted saporin conjugates that “piggyback” on to your primary targeting agent Controls are a vital part of the scientific procedure. These control conjugates are the same molecular weight, consist of similar, comparable materials and are
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Beta Program Video
Beta Program Video An introduction to our Beta Product Program. What is it and what are the benefits?
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