Author name: Kristen Hartman

Cortical cholinergic inputs mediate processing capacity: Effects of 192 IgG-saporin-induced lesions on olfactory span performance.

Turchi J, Sarter M (2000) Cortical cholinergic inputs mediate processing capacity: Effects of 192 IgG-saporin-induced lesions on olfactory span performance. Eur J Neurosci 12:4505-4514. Summary: Many experiments support the theory that the basal forebrain (BF) is involved in major aspects of attention that influence learning and memory. Elimination of cholinergic neurons in the BF by […]

Cortical cholinergic inputs mediate processing capacity: Effects of 192 IgG-saporin-induced lesions on olfactory span performance. Read More »

Non-linear cortico-cortical interactions modulated by cholinergic afferences from the rat basal forebrain.

Villa AEP, Tetko IV, Dutoit P, Vantini G (2000) Non-linear cortico-cortical interactions modulated by cholinergic afferences from the rat basal forebrain. BioSystems 58:219-228. doi: 10.1016/s0303-2647(00)00126-x Summary: Elimination of the cholinergic neurons of the basal forebrain (BF) is an excellent model for some aspects of Alzheimer’s Disease (AD). 192-Saporin (Cat. #IT-01) is a very effective tool

Non-linear cortico-cortical interactions modulated by cholinergic afferences from the rat basal forebrain. Read More »

Central cholinergic depletion induced by 192 IgG-saporin alleviates the sedative effects of propofol in rats.

Pain L, Jeltsch H, Lehmann O, Lazarus C, Laalou FZ, Cassel JC (2000) Central cholinergic depletion induced by 192 IgG-saporin alleviates the sedative effects of propofol in rats. Brit J Anaesth 85(6):869-873. doi: 10.1093/bja/85.6.869 Summary: In order to examine the effect of cholinergic depletion on the sedative potency of propofol in rats the authors injected

Central cholinergic depletion induced by 192 IgG-saporin alleviates the sedative effects of propofol in rats. Read More »

Neuronal lesioning with axonally transported toxins.

Wiley RG, Kline IV RH (2000) Neuronal lesioning with axonally transported toxins. J Neurosci Methods 103:73-82. doi: 10.1016/S0165-0270(00)00297-1 Summary: Functional neuroanatomy studies have long utilized lesioning. Given the complexity of heterogeneous neuron populations conventional lesioning methods have proved relatively crude, and have provided limited information. Wiley and Kline detail some of the immunotoxins utilizing saporin

Neuronal lesioning with axonally transported toxins. Read More »

Effects of intra-basalis infusion of d-cycloserine upon sustained attention performance in rats.

Sarter M, Turchi J (2000) Effects of intra-basalis infusion of d-cycloserine upon sustained attention performance in rats. Neuroscience 2000 Abstracts 837.10. Society for Neuroscience, New Orleans, LA. Summary: As basal forebrain NMDA receptor modulation has been hypothesized to play a significant role in tasks taxing attentional processes (Turchi & Sarter 1999), positive NMDA receptor modulation

Effects of intra-basalis infusion of d-cycloserine upon sustained attention performance in rats. Read More »

Nucleus basalis magnocellularis and enriched housing: Partners in neural patterns of attention?

Westhead C, Saari RK, Morrison P, Williams PT, Saari MJ (2000) Nucleus basalis magnocellularis and enriched housing: Partners in neural patterns of attention?. Neuroscience 2000 Abstracts 837.3. Society for Neuroscience, New Orleans, LA. Summary: Diminished levels of cholinergic markers in the brains of Alzheimer’s patients led to the belief that central cholinergic systems play a

Nucleus basalis magnocellularis and enriched housing: Partners in neural patterns of attention? Read More »

Attentional demand-related alterations in medial prefrontal neural activity of aged rats during sustained visual attention.

Gill TM, Yurrita MM, Givens B (2000) Attentional demand-related alterations in medial prefrontal neural activity of aged rats during sustained visual attention. Neuroscience 2000 Abstracts 837.6. Society for Neuroscience, New Orleans, LA. Summary: Neural activity within the medial prefrontal cortex (mPFC) exhibits distinct relationships to sustained visual attentional performance in young male Long-Evans rats. Cortical

Attentional demand-related alterations in medial prefrontal neural activity of aged rats during sustained visual attention. Read More »

Responses of spinal dorsal horn neurons to capsaicin following intrathecal pretreatment with substance p-saporin toxin.

Khasabov SG, Rogers SD, Mantyh PW, Simone DA (2000) Responses of spinal dorsal horn neurons to capsaicin following intrathecal pretreatment with substance p-saporin toxin. Neuroscience 2000 Abstracts 635.13. Society for Neuroscience, New Orleans, LA. Summary: Intrathecal (i.t.) application of the cytotoxic substance P-saporin (SP-SAP) conjugate is internalized by dorsal horn neurons expressing the SP receptor

Responses of spinal dorsal horn neurons to capsaicin following intrathecal pretreatment with substance p-saporin toxin. Read More »

Contribution of IB4-positive sensory neurons to NGF-induced hyperalgesia in the rat.

Tarpley JW, Martin WJ, Baldwin BS, Forrest MJ, MacIntyre DE (2000) Contribution of IB4-positive sensory neurons to NGF-induced hyperalgesia in the rat. Neuroscience 2000 Abstracts 633.18. Society for Neuroscience, New Orleans, LA. Summary: Sensory information is transmitted from the periphery to the spinal cord by distinct subsets of primary afferent neurons, including two major classes

Contribution of IB4-positive sensory neurons to NGF-induced hyperalgesia in the rat. Read More »

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