Author name: Kristen Hartman

Targeting serotonin re-uptake transporter (SERT) -expressing cells with a monoclonal antibody to an epitope from the extracellular domain of SERT: Results with a saporin conjugate.

Lappi D, Kohls M, Majer K, Russell B, Blakely R Richerson G (2002) Targeting serotonin re-uptake transporter (SERT) -expressing cells with a monoclonal antibody to an epitope from the extracellular domain of SERT: Results with a saporin conjugate. FENS 2002 Abstracts 049.7. Federation of European Neuroscience Societies, Paris, France. PMID: 0 Related Products: Antibody to […]

Targeting serotonin re-uptake transporter (SERT) -expressing cells with a monoclonal antibody to an epitope from the extracellular domain of SERT: Results with a saporin conjugate. Read More »

Effects of mice EGF-responsive neural stem cells grafts and fetal septal cells grafts implanted into the dorsal hippocampus of rats after immunotoxic denervation

Jeltsch H, Aloy E, Schimchowitsch S, Caillard S, Mohier E Cassel JC (2002) Effects of mice EGF-responsive neural stem cells grafts and fetal septal cells grafts implanted into the dorsal hippocampus of rats after immunotoxic denervation. FENS 2002 Abstracts 141.13. Federation of European Neuroscience Societies, Paris, France. Related Products: 192-IgG-SAP (Cat. #IT-01)

Effects of mice EGF-responsive neural stem cells grafts and fetal septal cells grafts implanted into the dorsal hippocampus of rats after immunotoxic denervation Read More »

Selective lesioning of the developing cholinergic and noradrenergic systems: Anatomical, neurochemical and functional effects

Leanza G, Cataudella T (2002) Selective lesioning of the developing cholinergic and noradrenergic systems: Anatomical, neurochemical and functional effects. FENS 2002 Abstracts 151.12. Federation of European Neuroscience Societies, Paris, France. Related Products: Anti-DBH-SAP (Cat. #IT-03)

Selective lesioning of the developing cholinergic and noradrenergic systems: Anatomical, neurochemical and functional effects Read More »

Selective neonatal lesions of the basal forebrain cholinergic neurons impair memory of socially-transmitted food preferences in adult rats

Ricceri L, Moles A, Scattoni ML, Calamandrei G (2002) Selective neonatal lesions of the basal forebrain cholinergic neurons impair memory of socially-transmitted food preferences in adult rats. FENS 2002 Abstracts 209.4. Federation of European Neuroscience Societies, Paris, France. Related Products: 192-IgG-SAP (Cat. #IT-01)

Selective neonatal lesions of the basal forebrain cholinergic neurons impair memory of socially-transmitted food preferences in adult rats Read More »

Impairment and restoration of spatial abilities following 192 IgG-saporin or quisqualic acid lesions of the median septum in rats

Brandner C (2002) Impairment and restoration of spatial abilities following 192 IgG-saporin or quisqualic acid lesions of the median septum in rats. FENS 2002 Abstracts 210.3. Federation of European Neuroscience Societies, Paris, France. Related Products: 192-IgG-SAP (Cat. #IT-01)

Impairment and restoration of spatial abilities following 192 IgG-saporin or quisqualic acid lesions of the median septum in rats Read More »

Selective lesion of cholinergic neurons in the medial septum by 192 IgG-saporin impairs learning in a delayed matching to position T-maze paradigm.

Johnson DA, Zambon NJ, Gibbs RB (2002) Selective lesion of cholinergic neurons in the medial septum by 192 IgG-saporin impairs learning in a delayed matching to position T-maze paradigm. Brain Res 943(1):132-141. doi: 10.1016/s0006-8993(02)02623-9 Summary: The authors investigated the effects of selective cholinergic depletion in the medial septum on a spatial memory (DMP) task. Direct

Selective lesion of cholinergic neurons in the medial septum by 192 IgG-saporin impairs learning in a delayed matching to position T-maze paradigm. Read More »

Combined 192 IgG-saporin and 5,7-dihydroxytryptamine lesions in the male rat brain: A neurochemical and behavioral study.

Lehmann O, Jeltsch H, Lazarus C, Tritschler L, Bertrand F, Cassel JC (2002) Combined 192 IgG-saporin and 5,7-dihydroxytryptamine lesions in the male rat brain: A neurochemical and behavioral study. Pharmacol Biochem Behav 72(4):899-912. doi: 10.1016/s0091-3057(02)00752-9 Summary: Female rats treated with both 192-Saporin (Cat #IT-01) and 5,7-DHT exhibited working memory impairments that were not seen with

Combined 192 IgG-saporin and 5,7-dihydroxytryptamine lesions in the male rat brain: A neurochemical and behavioral study. Read More »

5,7-DHT-induced hippocampal 5-HT depletion attenuates behavioural deficits produced by 192 IgG-saporin lesions of septal cholinergic neurons in the rat.

Lehmann O, Bertrand F, Jeltsch H, Morer M, Lazarus C, Will B, Cassel JC (2002) 5,7-DHT-induced hippocampal 5-HT depletion attenuates behavioural deficits produced by 192 IgG-saporin lesions of septal cholinergic neurons in the rat. Eur J Neurosci 15(12):1991-2006. doi: 10.1046/j.1460-9568.2002.02037.x Summary: Although past data has shown that the cholinergic system of the basal forebrain is

5,7-DHT-induced hippocampal 5-HT depletion attenuates behavioural deficits produced by 192 IgG-saporin lesions of septal cholinergic neurons in the rat. Read More »

Cover Article: Saporin Immunotoxins for Treating Human Hematological Malignancies

News Article /

Contributed by David J Flavell, PhD, The Simon Flavell Leukaemia Research Unit, Division of Cancer Sciences, University of Southampton Medical School, United Kingdom. I have asked Dr. Flavell to contribute an article on the clinical use of his saporin immunotoxins. Dr. Flavell’s research unit is named after his son, who died from leukemia. At that

Cover Article: Saporin Immunotoxins for Treating Human Hematological Malignancies Read More »

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