Provencio I, Rodriguez IR, Jiang G, Hayes WP, Moreira EF, Rollag MD (2000) A novel human opsin in the inner retina. J Neurosci 20(2):600-605. doi: 10.1523/JNEUROSCI.20-02-00600.2000 PMID: 10632589 Summary: Provencio and colleagues found that melanopsin is also present in mouse retina, specifically in ganglion cells, and that it mediates non-visual photoreceptive tasks. Related Products: Melanopsin […]
A novel human opsin in the inner retina. Read More »
Winkler J, Ramirez GA, Thal LJ, Waite JJ (2000) Nerve growth factor (NGF) augments cortical and hippocampal cholinergic functioning after p75NGF receptor-mediated deafferentation but impairs inhibitory avoidance and induces fear-related behaviors. J Neurosci 20:834-844. doi: 10.1523/JNEUROSCI.20-02-00834.2000 Usage: 192-SAP (Cat. #IT-01) 1.0 or 2.7 µg in 10 µl, intracerebroventricular Related Products: 192-IgG-SAP (Cat. #IT-01)
Friedrich MJ (2000) Loss of nerve: a molecular approach to better treatment of chronic pain. JAMA 283(2):187-188. doi: 10.1001/jama.283.2.187 Summary: The use of SP-SAP (Cat. #IT-07) as a promising new method for chronic pain relief is discussed in this review article. Chronic pain has classically been treated in ways that frequently have adverse effects on
Loss of nerve: a molecular approach to better treatment of chronic pain. Read More »
Bassant MH, Poindessous-Jazat F, Schmidt BH (2000) Sustained effect of metrifonate on cerebral glucose metabolism after immunolesion of basal forebrain cholinergic neurons in rats. Eur J Pharmacol 387:151-162. doi: 10.1016/s0014-2999(99)00742-6 Usage: 192-SAP (Cat. #IT-01) 134 ng in 0.2 μl, basal forebrain Related Products: 192-IgG-SAP (Cat. #IT-01)
Kohls MD, Lappi DA (2000) Mab-ZAP: A tool for evaluating antibody efficacy for use in an immunotoxin. BioTechniques 28(1):162-165. doi: 10.2144/00281pf01 Summary: Immunotoxins are useful tools for elimination of specific cell populations in vitro and in vivo for research and therapeutic applications. One of the factors limiting the use of immunotoxins is the selection of an
Mab-ZAP: A tool for evaluating antibody efficacy for use in an immunotoxin. Read More »
Lehmann O, Jeltsch H, Lehnardt O, Pain L, Lazarus C, Cassel JC (2000) Combined lesions of cholinergic and serotonergic neurons in the rat brain using 192 IgG-Saporin and 5,7-dihydroxytryptamine: neurochemical and behavioural characterization. Eur J Neurosci 12:67-79. doi: 10.1046/j.1460-9568.2000.00881.x Summary: Lesioning of septohippocampal pathways has often been used as a model for Alzheimer’s disease because
Sorger D, Schliebs R, Kampfer I, Rossner S, Heinicke J, Dannenberg C, Georgi P (2000) In vivo [125I]-iodobenzovesamicol binding reflects cortical cholinergic deficiency induced by specific immunolesion of rat basal forebrain cholinergic system. Nucl Med Biol 27:23-31. doi: 10.1016/s0969-8051(99)00087-6 Usage: 192-SAP (Cat. #IT-01), 2 µg into each lateral ventricle Related Products: 192-IgG-SAP (Cat. #IT-01)
Sarter M, Bruno JP (2000) Cortical cholinergic inputs mediating arousal, attentional processing and dreaming: Differential afferent regulation of the basal forebrain by telencephalic and brainstem afferents. Neuroscience 95(4):933-952. doi: 10.1016/s0306-4522(99)00487-x Objective: To examine the cortical cholinergic inputs mediating arousal, specific attentional functions and rapid eye movement sleep-associated dreaming. Summary: The incorporation of persistent changes in
Wiley RG, Lappi DA (1999) Targeting neurokinin-1 receptor-expressing neurons with [Sar9, Met(O2)11] substance P-saporin. Neurosci Lett 277(1):1-4. doi: 10.1016/s0304-3940(99)00846-0 Related Products: SSP-SAP (Cat. #IT-11)
Wrenn C, Lappi DA, Wiley RG (1999) Threshold relationship between lesion extent of the cholinergic basal forebrain in the rat and working memory impairment in the radial maze. Brain Res 847(2):284-298. doi: 10.1016/s0006-8993(99)02099-5 Related Products: 192-IgG-SAP (Cat. #IT-01)