Cortical cholinergic inputs mediating arousal, attentional processing and dreaming: Differential afferent regulation of the basal forebrain by telencephalic and brainstem afferents.

Sarter M, Bruno JP (2000) Cortical cholinergic inputs mediating arousal, attentional processing and dreaming: Differential afferent regulation of the basal forebrain by telencephalic and brainstem afferents. Neuroscience 95(4):933-952. doi: 10.1016/s0306-4522(99)00487-x

Objective: To examine the cortical cholinergic inputs mediating arousal, specific attentional functions and rapid eye movement sleep-associated dreaming.

Summary: The incorporation of persistent changes in cortical information processing as a result of paired stimulation of cholinergic and sensory inputs into current theories about the cognitive functions of cortical ACh awaits more information, particularly with reference to the temporal dynamic properties of the effects of endogenously released ACh on cortical information processing.

Related Products: 192-IgG-SAP (Cat. #IT-01)

See Also:

• McGaughy J et al. Behavioral vigilance following infusions of 192 IgG-saporin into the basal forebrain: selectivity of the behavioral impairment and relation to cortical AChE-positive fiber density. Behav Neurosci 110:247-265, 1996.
• McGaughy J et al. Sustained attention performance in rats with intracortical infusions of 192 IgG-saporin-induced cortical cholinergic deafferentation: effects of physostigmine and FG 7142. Behav Neurosci 112(6):1519-1525, 1998.