Author name: Kristen Hartman

Microfluidic nanomaterials: From synthesis to biomedical applications.

Illath K, Kar S, Gupta P, Shinde A, Wankhar S, Tseng FG, Lim KT, Nagai M, Santra TS (2022) Microfluidic nanomaterials: From synthesis to biomedical applications. Biomaterials 280:121247. doi: 10.1016/j.biomaterials.2021.121247 Objective: To evaluate the current state of the controlled synthesis of nanomaterials using microfluidic devices. Summary: In summary, inherent features of microfluidics enabled the controlled […]

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The role of the patch compartment of striatum in reward-driven behaviors

Ahn J, Christy DJ, Horner K (2021) The role of the patch compartment of striatum in reward-driven behaviors. Neuroscience 2021 Abstracts P747/06. Society for Neuroscience, Virtual. Summary: The striatum is a neural structure that plays a critical role in cognitive functions, behavioral decision-making, and reward generation. The striatum exhibits a heterogeneous composition, containing neurons belonging

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Contribution of small diameter non-peptidergic primary afferent neurons to central neuropathic pain in a new, more clinically relevant mouse model of multiple sclerosis

Nguyen KL, Lamerand SR, Deshpande RP, Taylor BK (2021) Contribution of small diameter non-peptidergic primary afferent neurons to central neuropathic pain in a new, more clinically relevant mouse model of multiple sclerosis. Neuroscience 2021 Abstracts P377/07. Society for Neuroscience, Virtual. Summary: Over 50% of multiple sclerosis (MS) patients suffer from neuropathic pain (MSNP). Current treatments

Contribution of small diameter non-peptidergic primary afferent neurons to central neuropathic pain in a new, more clinically relevant mouse model of multiple sclerosis Read More »

A brief history of saporin and its contributions to neuroscience

Shramm PA, Ancheta LR, Bouajram R, Lappi DA (2021) A brief history of saporin and its contributions to neuroscience. Neuroscience 2021 Abstracts J002.11. Society for Neuroscience, Virtual. Summary: When investigating the origins of targeted toxins (a drug, therapy, or scientific tool directed to a unique extracellular target), an appropriate place to begin is with the

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Effects of age on sexually dimorphic food protection behavior associated with hippocampal cholinergic deafferentation.

Osterlund Oltmanns JR, Schaeffer EA, Blackwell AA, Pietrucha SA, Yang H, Tasi S, Kartje GL, Wallace D (2021) Effects of age on sexually dimorphic food protection behavior associated with hippocampal cholinergic deafferentation. Neuroscience 2021 Abstracts P210.07. Society for Neuroscience, Virtual. Summary: Loss of hippocampal cholinergic projection originating from basal forebrain structures has been associated with

Effects of age on sexually dimorphic food protection behavior associated with hippocampal cholinergic deafferentation. Read More »

Toxic substance-induced hippocampal neurodegeneration in rodents as model of Alzheimer’s dementia

Nurmasitoh T, Sari DCR, Susilowati R (2021) Toxic substance-induced hippocampal neurodegeneration in rodents as model of Alzheimer’s dementia. Open Access Maced J Med Sci [Internet] 9(F):523. Summary: In this review, the authors discussed hippocampal neurodegeneration rodent animal models of Alzheimer’s Dementia and their induction via a toxic substance. Between 2016-2021, 80 studies were reported with

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Light-controlled elimination of PD-L1+ cells

Wong JJW, Selbo PK (2021) Light-controlled elimination of PD-L1+ cells. J Photochem Photobiol B 225:112355. doi: 10.1016/j.jphotobiol.2021.112355 Objective: To investigate novel strategies that simultaneously target both tumor cells and immunosuppressive cells in the tumor microenvironment. The focus was on the evaluation in vitro of Anti-PD-L1-SAP combined with photochemical internalization (PCI) as a therapeutic strategy to

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Violet light modulates the central nervous system to regulate memory and mood

Sasaki N, Gusain P, Hayano M, Sugaya T, Tonegawa N, Hatanaka Y, Tamura R, Okuyama K, Osada H, Ban N, Mitsukura Y, Lang RA, Mimura M, Tsubota K (2021) Violet light modulates the central nervous system to regulate memory and mood. bioRxiv 2021.11.02.466604. doi: 10.1101/2021.11.02.466604 Related Products: Melanopsin Rabbit Polyclonal, affinity-purified (Cat. #AB-N39)

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Hydrophobicity-tuned anion responsiveness underlies endosomolytic cargo delivery mediated by amphipathic vehicle peptides.

Chen X, Liu H, Li A, Ji S, Fei H (2021) Hydrophobicity-tuned anion responsiveness underlies endosomolytic cargo delivery mediated by amphipathic vehicle peptides. J Biol Chem 297(6):101364. doi: 10.1016/j.jbc.2021.101364 Objective: The study focuses on hydrophobicity and a structure-function strategy to evolve a template peptide for endosomolytic cargo delivery. Summary: The peptide LP6 could dramatically promote

Hydrophobicity-tuned anion responsiveness underlies endosomolytic cargo delivery mediated by amphipathic vehicle peptides. Read More »

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