Author name: Kristen Hartman

Evaluation of cholinergic markers in Alzheimer’s disease and in a model of cholinergic deficit.

Gil-Bea FJ, Garcia-Alloza M, Dominguez J, Marcos B, Ramirez MJ (2005) Evaluation of cholinergic markers in Alzheimer’s disease and in a model of cholinergic deficit. Neurosci Lett 375(1):37-41. doi: 10.1016/j.neulet.2004.10.062 Summary: Several markers of cholinergic function may be able to predict cognitive deficits due to disorders such as Alzheimer’s disease. The authors compared baseline measurements […]

Evaluation of cholinergic markers in Alzheimer’s disease and in a model of cholinergic deficit. Read More »

Purkinje cell loss by OX7-saporin impairs excitatory and inhibitory eyeblink conditioning.

Nolan BC, Freeman JH Jr (2005) Purkinje cell loss by OX7-saporin impairs excitatory and inhibitory eyeblink conditioning. Behav Neurosci 119(1):190-201. doi: 10.1037/0735-7044.119.1.190 Summary: Although the contributions of the cortical cerebellum to eyeblink-conditioned excitation have been extensively investigated, involvement in inhibition of this reflex is unclear. After intracerebroventricular infusions of 15.0 µg of OX7-SAP (Cat. #IT-02),

Purkinje cell loss by OX7-saporin impairs excitatory and inhibitory eyeblink conditioning. Read More »

Ablation of a population of neurons in the dorsal horn of the spinal cord is insufficient to induce sprouting of touch responsive myelinated afferents into the innervation territory of pain sensitive unmyelinated afferents.

Whiteside GT, Woods ME, Pearson MS, Pomonis JD, Turchin PI, Walker K (2005) Ablation of a population of neurons in the dorsal horn of the spinal cord is insufficient to induce sprouting of touch responsive myelinated afferents into the innervation territory of pain sensitive unmyelinated afferents. Med Hypotheses Res 2:275-282. Related Products: SP-SAP (Cat. #IT-07)

Ablation of a population of neurons in the dorsal horn of the spinal cord is insufficient to induce sprouting of touch responsive myelinated afferents into the innervation territory of pain sensitive unmyelinated afferents. Read More »

Spinal neurons that express NK-1 receptors modulate descending controls that project through the dorsolateral funiculus.

Khasabov SG, Ghilardi JR, Mantyh PW, Simone DA (2005) Spinal neurons that express NK-1 receptors modulate descending controls that project through the dorsolateral funiculus. J Neurophysiol 93(2):998-1006. doi: 10.1152/jn.01160.2003 Summary: The involvement of neurokinin-1 receptor-expressing neurons in the spinal cord with the ascending systems of hyperalgesia and central sensitization has been well established. The authors

Spinal neurons that express NK-1 receptors modulate descending controls that project through the dorsolateral funiculus. Read More »

The effect of central cholinergic and noradrenergic denervation on hippocampal sympathetic ingrowth and apoptosis-like reactivity in the rat.

Harrell LE, Parsons DS, Kolasa K (2005) The effect of central cholinergic and noradrenergic denervation on hippocampal sympathetic ingrowth and apoptosis-like reactivity in the rat. Brain Res 1033(1):68-77. doi: 10.1016/j.brainres.2004.11.021 Summary: Cholinergic denervation of the hippocampus is followed by ingrowth of peripheral sympathetic fibers originating from the superior cervical ganglion. The authors injected 1 µg

The effect of central cholinergic and noradrenergic denervation on hippocampal sympathetic ingrowth and apoptosis-like reactivity in the rat. Read More »

Effects of cholinergic deafferentation of the rhinal cortex on visual recognition memory in monkeys.

Turchi J, Saunders RC, Mishkin M (2005) Effects of cholinergic deafferentation of the rhinal cortex on visual recognition memory in monkeys. Proc Natl Acad Sci U S A 102(6):2158-2161. doi: 10.1073/pnas.0409708102 Summary: The rhinal cortex has been shown to play a critical role in recognition memory. The investigators examined the effect of eliminating cholinergic input

Effects of cholinergic deafferentation of the rhinal cortex on visual recognition memory in monkeys. Read More »

Hebb-Williams performance and scopolamine challenge in rats with partial immunotoxic hippocampal cholinergic deafferentation.

Marques Pereira P, Cosquer B, Schimchowitsch S, Cassel JC (2005) Hebb-Williams performance and scopolamine challenge in rats with partial immunotoxic hippocampal cholinergic deafferentation. Brain Res Bull 64(5):381-394. doi: 10.1016/j.brainresbull.2004.09.007 Summary: Much of the recent work done on the role of cholinergic neurons in the hippocampus has been focused on detecting subtle learning deficits. In this

Hebb-Williams performance and scopolamine challenge in rats with partial immunotoxic hippocampal cholinergic deafferentation. Read More »

An opposing time-dependent immune-modulating effect of the sympathetic nervous system conferred by altering the cytokine profile in the local lymph nodes and spleen of mice with type II collagen-induced arthritis.

Harle P, Mobius D, Carr DJ, Scholmerich J, Straub RH (2005) An opposing time-dependent immune-modulating effect of the sympathetic nervous system conferred by altering the cytokine profile in the local lymph nodes and spleen of mice with type II collagen-induced arthritis. Arthritis Rheum 52:1305-1313. doi: 10.1002/art.20987 Summary: In this work the authors examined the role

An opposing time-dependent immune-modulating effect of the sympathetic nervous system conferred by altering the cytokine profile in the local lymph nodes and spleen of mice with type II collagen-induced arthritis. Read More »

Targeting Tools: Anti-ChAT

ATS is pleased to present a polyclonal antibody specific for ChAT protein. Choline acetyltransferase (ChAT) catalyzes the synthesis of the neurotransmitter acetylcholine (ACh) from choline and acetyl-CoA in cholinergic neurons. ChAT serves as a specific marker for cholinergic neurons in both the peripheral and central nervous systems. Dysfunction of cholinergic neurons underlies aspects of clinical

Targeting Tools: Anti-ChAT Read More »

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