Author name: Kristen Hartman

The basal forebrain cholinergic system is essential for cortical plasticity and functional recovery following brain injury

Conner JM, Chiba AA, Tuszynski MH (2004) The basal forebrain cholinergic system is essential for cortical plasticity and functional recovery following brain injury. Neuroscience 2004 Abstracts 685.12. Society for Neuroscience, San Diego, CA. Summary: Localized damage to the motor cortex typically results in impaired motor function. Functional recovery following focal brain injury presumably requires the […]

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Cell-body lesions of basal forebrain impair reversal learning but not attentional set-shifting in rats

Tait DS, Brown VJ (2004) Cell-body lesions of basal forebrain impair reversal learning but not attentional set-shifting in rats. Neuroscience 2004 Abstracts 779.12. Society for Neuroscience, San Diego, CA. Summary: There is considerable evidence for a role of basal forebrain acetylcholine in a wide range of attentional tasks (see Sarter & Bruno, 2000, Neurosci, 95:933-952),

Cell-body lesions of basal forebrain impair reversal learning but not attentional set-shifting in rats Read More »

Attention, uncertainty, and acetylcholine: Effects of nucleus basalis cholinergic lesions on probabilistic inference

Cordova CA, Yu AJ, Chiba AA (2004) Attention, uncertainty, and acetylcholine: Effects of nucleus basalis cholinergic lesions on probabilistic inference. Neuroscience 2004 Abstracts 779.13. Society for Neuroscience, San Diego, CA. Summary: Animal investigations suggest that the basal forebrain corticopetal cholinergic system helps to regulate attention to unpredictable events. In light of these findings, computational theorists

Attention, uncertainty, and acetylcholine: Effects of nucleus basalis cholinergic lesions on probabilistic inference Read More »

Behavioral characteristics of pedunculopontine tegmental nucleus lesioned and nucleus basalis magnocellularis lesioned rats in a test of vigilance

Taylor CL, Rostron PR, Latimer MP, Winn P (2004) Behavioral characteristics of pedunculopontine tegmental nucleus lesioned and nucleus basalis magnocellularis lesioned rats in a test of vigilance. Neuroscience 2004 Abstracts 780.4. Society for Neuroscience, San Diego, CA. Summary: Previous work has shown pedunculopontine tegmental nucleus (PPTg) lesioned rats make more omissions on a vigilance task

Behavioral characteristics of pedunculopontine tegmental nucleus lesioned and nucleus basalis magnocellularis lesioned rats in a test of vigilance Read More »

Neurokinin 1 receptor expressing interneurons of the BLA regulate anxiety-like responses in the rat

Truitt WA, Dietrich AD, Fitz SD, Minick PE, Shekhar A (2004) Neurokinin 1 receptor expressing interneurons of the BLA regulate anxiety-like responses in the rat. Neuroscience 2004 Abstracts 782.5. Society for Neuroscience, San Diego, CA. Summary: The Basolateral Nucleus of the Amygdala (BLA) has been implicated in the regulation and development of anxiety. In general,

Neurokinin 1 receptor expressing interneurons of the BLA regulate anxiety-like responses in the rat Read More »

Effects of neonatal cholinergic lesions on fear conditioning in 18-day-old rats

Ricceri L, Scattoni ML, Cutuli D, Calamandrei G (2004) Effects of neonatal cholinergic lesions on fear conditioning in 18-day-old rats. Neuroscience 2004 Abstracts 436.9. Society for Neuroscience, San Diego, CA. Summary: We have previously shown that neonatal intracerebroventricular (icv) injections of the selective cholinergic immunotoxin 192 IgG-saporin on postnatal day (pnd) 7 induces behavioural alterations

Effects of neonatal cholinergic lesions on fear conditioning in 18-day-old rats Read More »

Electrophysiological profile of IgG192saporin-lesioned rats in the pilocarpine model of epilepsy

Benassi SK, Blanco MM, Mello LE (2004) Electrophysiological profile of IgG192saporin-lesioned rats in the pilocarpine model of epilepsy. Neuroscience 2004 Abstracts 452.14. Society for Neuroscience, San Diego, CA. Summary: In order to investigate the importance of the basal forebrain cholinergic reorganization to the epileptogenesis process, adult male Wistar EPM-1 rats (180-220g) were subjected to status

Electrophysiological profile of IgG192saporin-lesioned rats in the pilocarpine model of epilepsy Read More »

Investigation of the functional role of non-peptidergic primary afferent sensory fibres in the transmission of pain related information

Bailey AL, Bennett G, Ribeiro-da-Silva A (2004) Investigation of the functional role of non-peptidergic primary afferent sensory fibres in the transmission of pain related information. Neuroscience 2004 Abstracts 484.1. Society for Neuroscience, San Diego, CA. Summary: It is well established that small diameter, unmyelinated, primary afferent C-fibres can be divided into two neurochemically defined populations,

Investigation of the functional role of non-peptidergic primary afferent sensory fibres in the transmission of pain related information Read More »

Effects of cholinergic deafferentation of prefrontal cortex on working memory: A convergence of behavioral and modeling results

McGaughy JA, Koene R, Eichenbaum HB, Hasselmo ME (2004) Effects of cholinergic deafferentation of prefrontal cortex on working memory: A convergence of behavioral and modeling results. Neuroscience 2004 Abstracts 551.7. Society for Neuroscience, San Diego, CA. Summary: In humans, the prefrontal and medial temporal lobe areas are differentially activated during working memory dependent upon the

Effects of cholinergic deafferentation of prefrontal cortex on working memory: A convergence of behavioral and modeling results Read More »

A novel mouse model for Parkinson’s disease using an immunotoxin directed at the dopamine transporter

Stead S, Doering LC (2004) A novel mouse model for Parkinson’s disease using an immunotoxin directed at the dopamine transporter. Neuroscience 2004 Abstracts 563.1. Society for Neuroscience, San Diego, CA. Summary: Current laboratory models of Parkinson’s disease utilize neurotoxins directed at midbrain dopamine neurons to mimic nigro-striatal dopaminergic neuron degeneration. To date, however, there is

A novel mouse model for Parkinson’s disease using an immunotoxin directed at the dopamine transporter Read More »

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