Author name: Kristen Hartman

Sensory experience determines enrichment-induced plasticity in rat auditory cortex.

Percaccio CR, Pruette AL, Mistry ST, Chen YH, Kilgard MP (2007) Sensory experience determines enrichment-induced plasticity in rat auditory cortex. Brain Res 1174:76-91. doi: 10.1016/j.brainres.2007.07.062 Summary: Animals housed in enriched environments display numerous signs of good neural health. In this work the authors examined the role acetylcholine plays in this plasticity. 2.6 µg of 192-IgG-SAP […]

Sensory experience determines enrichment-induced plasticity in rat auditory cortex. Read More »

Featured Article: Inducing central sensitization with a substance P/ cholera toxin conjugate

Caudle RM (2007) Featured Article: Inducing central sensitization with a substance P/ cholera toxin conjugate. Targeting Trends 8(4) Related Products: SP-SAP (Cat. #IT-07), SP-CTA (Cat. #IT-39) Read the featured article in Targeting Trends. See Also: Caudle RM Sensitization of spinal cord nociceptive neurons with a conjugate of substance P and cholera toxin. BMC Neuroscience 8:30,

Featured Article: Inducing central sensitization with a substance P/ cholera toxin conjugate Read More »

Cover Article: Inducing Central Sensitization with a Substance P/ Cholera Toxin Conjugate

Contributed by Robert M. Caudle, Ph.D.University of Florida College of Dentistry, Gainesville, FL 32610 A substantial amount of work with Advanced Targeting Systems’ substance P/saporin conjugate (SP-SAP, Cat. #IT-07) has demonstrated that neurokinin-1 (NK1) receptor-expressing neurons in the spinal cord and brain stem are necessary for the full expression of central sensitization following a peripheral

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Neonatal basal forebrain cholinergic hypofunction affects ultrasonic vocalizations and fear conditioning responses in preweaning rats.

Ricceri L, Cutuli D, Venerosi A, Scattoni ML, Calamandrei G (2007) Neonatal basal forebrain cholinergic hypofunction affects ultrasonic vocalizations and fear conditioning responses in preweaning rats. Behav Brain Res 183:111-117. doi: 10.1016/j.bbr.2007.05.035 Summary: In order to expand on previous work investigating the effect of early cholinergic lesions on processing of aversive stimuli the authors administered

Neonatal basal forebrain cholinergic hypofunction affects ultrasonic vocalizations and fear conditioning responses in preweaning rats. Read More »

Selective hippocampal cholinergic deafferentation impairs self-movement cue use during a food hoarding task.

Martin MM, Wallace DG (2007) Selective hippocampal cholinergic deafferentation impairs self-movement cue use during a food hoarding task. Behav Brain Res 183:78-86. doi: 10.1016/j.bbr.2007.05.026 Summary: There are conflicting data surrounding the role of the septohippocampal system in spatial orientation. The authors suggest that the presence of spatial clues during some of these tests may skew

Selective hippocampal cholinergic deafferentation impairs self-movement cue use during a food hoarding task. Read More »

Selective immunolesion of cholinergic neurons leads to long-term changes in 5-HT2A receptor levels in hippocampus and frontal cortex.

Severino M, Pedersen AF, Trajkovska V, Christensen E, Lohals R, Veng LM, Knudsen GM, Aznar S (2007) Selective immunolesion of cholinergic neurons leads to long-term changes in 5-HT2A receptor levels in hippocampus and frontal cortex. Neurosci Lett 428:47-51. doi: 10.1016/j.neulet.2007.09.026 Summary: Changes in several neurotransmitter systems, including serotonin and 5HT2A receptors, are associated with early

Selective immunolesion of cholinergic neurons leads to long-term changes in 5-HT2A receptor levels in hippocampus and frontal cortex. Read More »

Rituximab-CD20 complexes are shaved from Z138 mantle cell lymphoma cells in intravenous and subcutaneous SCID mouse models

Li Y, Williams ME, Cousar JB, Pawluczkowycz AW, Lindorfer MA, Taylor RP (2007) Rituximab-CD20 complexes are shaved from Z138 mantle cell lymphoma cells in intravenous and subcutaneous SCID mouse models. J Immunol 179(6):4263-4271. doi: 10.4049/jimmunol.179.6.4263 PMID: 17785867 Related Products: Antibody to Complement C3 (6C9) (Cat. #AB-V85)

Rituximab-CD20 complexes are shaved from Z138 mantle cell lymphoma cells in intravenous and subcutaneous SCID mouse models Read More »

Induction and survival of binucleated Purkinje neurons by selective damage and aging.

Magrassi L, Grimaldi P, Ibatici A, Corselli M, Ciardelli L, Castello S, Podesta M, Frassoni F, Rossi F (2007) Induction and survival of binucleated Purkinje neurons by selective damage and aging. J Neurosci 27:9885-9892. doi: 10.1523/JNEUROSCI.2539-07.2007 Summary: Donor bone marrow derived cells are thought to fuse with host Purkinje cells in small numbers to create

Induction and survival of binucleated Purkinje neurons by selective damage and aging. Read More »

Raphe Magnus Nucleus is involved in ventilatory but not hypothermic response to CO2.

Dias MB, Nucci TB, Margatho LO, Antunes-Rodrigues J, Gargaglioni LH, Branco LG (2007) Raphe Magnus Nucleus is involved in ventilatory but not hypothermic response to CO2. J Appl Physiol 103(5):1780-1788. doi: 10.1152/japplphysiol.00424.2007 Summary: In this work the authors investigated the role that serotonergic neurons in the Raphe Magnus Nucleus (RMg) play in ventilatory and thermal

Raphe Magnus Nucleus is involved in ventilatory but not hypothermic response to CO2. Read More »

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