Author name: Kristen Hartman

Endosialin protein expression and therapeutic target potential in human solid tumors: sarcoma versus carcinoma.

Rouleau C, Curiel M, Weber W, Smale R, Kurtzberg L, Mascarello J, Berger C, Wallar G, Bagley R, Honma N, Hasegawa K, Ishida I, Kataoka S, Thurberg BL, Mehraein K, Horten B, Miller G, Teicher BA (2008) Endosialin protein expression and therapeutic target potential in human solid tumors: sarcoma versus carcinoma. Clin Cancer Res 14:7223-7236. […]

Endosialin protein expression and therapeutic target potential in human solid tumors: sarcoma versus carcinoma. Read More »

Descending facilitation from the brainstem determines behavioural and neuronal hypersensitivity following nerve injury and efficacy of pregabalin.

Bee LA, Dickenson AH (2008) Descending facilitation from the brainstem determines behavioural and neuronal hypersensitivity following nerve injury and efficacy of pregabalin. Pain 140:209-223. doi: 10.1016/j.pain.2008.08.008 Summary: Rostral ventromedial medulla (RVM) facilitatory On cells are thought to be involved in the mechanisms that control chronic pain. Dermorphin-SAP (Cat. #IT-12, 3 pmol injected into the RVM

Descending facilitation from the brainstem determines behavioural and neuronal hypersensitivity following nerve injury and efficacy of pregabalin. Read More »

The ablation of hindbrain catecholamine neurons innervating medial hypothalamic nuclei abolishes glucoprivic feeding, but spares the orexigenic response to ghrelin

Emanuel AJ, Dinh TT, Ritter S (2008) The ablation of hindbrain catecholamine neurons innervating medial hypothalamic nuclei abolishes glucoprivic feeding, but spares the orexigenic response to ghrelin. Neuroscience 2008 Abstracts 85.2/RR15. Society for Neuroscience, Washington, DC. Summary: Ghrelin is an orexigenic peptide synthesized in the stomach and secreted during fasting. Receptors for ghrelin are present

The ablation of hindbrain catecholamine neurons innervating medial hypothalamic nuclei abolishes glucoprivic feeding, but spares the orexigenic response to ghrelin Read More »

Role of medial septum-diagonal band of Broca neurons in cognitive flexibility

Pang K, Janke K, Servatius RJ (2008) Role of medial septum-diagonal band of Broca neurons in cognitive flexibility. Neuroscience 2008 Abstracts 89.20/SS37. Society for Neuroscience, Washington, DC. Summary: Cholinergic and GABAergic neurons are major components of the septohippocampal pathway, and comparisons between the two neuronal populations are important for understanding the function of medial septum

Role of medial septum-diagonal band of Broca neurons in cognitive flexibility Read More »

192-IgG Saporin lesions of the medial septum or nucleus basalis magnocellularis disrupt exploratory trip organization

Wallace DG, Winter SS, Martin MM, Mcmillin JL (2008) 192-IgG Saporin lesions of the medial septum or nucleus basalis magnocellularis disrupt exploratory trip organization. Neuroscience 2008 Abstracts 90.15/SS57. Society for Neuroscience, Washington, DC. Summary: Previous work has demonstrated that rats use self-movement cues to organize their exploratory behavior. The hippocampus and several cortical areas have

192-IgG Saporin lesions of the medial septum or nucleus basalis magnocellularis disrupt exploratory trip organization Read More »

The role of orexin in sexual behavior and sexual reward of the male rat

Di Sebastiano AR, Yong-yow S, Coolen LM (2008) The role of orexin in sexual behavior and sexual reward of the male rat. Neuroscience 2008 Abstracts 97.4/UU18. Society for Neuroscience, Washington, DC. Summary: The hypothalamic neuropeptide orexin has been demonstrated to play a role in reward related to drugs of abuse and is potentially involved in

The role of orexin in sexual behavior and sexual reward of the male rat Read More »

The role of cholinergic basal forebrain neurons in adenosine-mediated homeostatic control of sleep: lessons from 192 IgG-saporin lesions.

Kalinchuk AV, McCarley RW, Stenberg D, Porkka-Heiskanen T, Basheer R (2008) The role of cholinergic basal forebrain neurons in adenosine-mediated homeostatic control of sleep: lessons from 192 IgG-saporin lesions. Neuroscience 157:238-253. doi: 10.1016/j.neuroscience.2008.08.040 Summary: The level of adenosine in the basal forebrain increases during sleep deprivation (SD). The cholinergic system of the basal forebrain is

The role of cholinergic basal forebrain neurons in adenosine-mediated homeostatic control of sleep: lessons from 192 IgG-saporin lesions. Read More »

Renal sympathoinhibition induced by hypernatremia: Involvement of A1 noradrenergic neurons.

Pedrino GR, Rosa DA, Korim WS, Cravo SL (2008) Renal sympathoinhibition induced by hypernatremia: Involvement of A1 noradrenergic neurons. Auton Neurosci 142(1-2):55-63. doi: 10.1016/j.autneu.2008.06.006 Summary: A1 noradrenergic neurons in the caudal ventrolateral medulla (CVLM) are thought to contribute to body fluid homeostasis and cardiovascular regulation. In order to examine the role these neurons play on

Renal sympathoinhibition induced by hypernatremia: Involvement of A1 noradrenergic neurons. Read More »

Noradrenergic inputs to the paraventricular hypothalamus contribute to hypothalamic-pituitary-adrenal axis and central Fos activation in rats after acute systemic endotoxin exposure.

Bienkowski MS, Rinaman L (2008) Noradrenergic inputs to the paraventricular hypothalamus contribute to hypothalamic-pituitary-adrenal axis and central Fos activation in rats after acute systemic endotoxin exposure. Neuroscience 156(4):1093-1102. doi: 10.1016/j.neuroscience.2008.08.011 Summary: Noradrenergic (NA) neurons in the central nervous system are activated during the immune response to systemic lipopolysaccharide (LPS). The authors tested whether these neurons

Noradrenergic inputs to the paraventricular hypothalamus contribute to hypothalamic-pituitary-adrenal axis and central Fos activation in rats after acute systemic endotoxin exposure. Read More »

Selective lesion of medial septal cholinergic neurons followed by a mini-stroke impairs spatial learning in rats.

Craig LA, Hong NS, Kopp J, McDonald RJ (2009) Selective lesion of medial septal cholinergic neurons followed by a mini-stroke impairs spatial learning in rats. Exp Brain Res 193(1):29-42. doi: 10.1007/s00221-008-1592-5 Summary: Recent work has suggested that reduced levels of acetylcholine, seen in Alzheimer’s disease patients, increases the susceptibility of hippocampal neurons to future challenges.

Selective lesion of medial septal cholinergic neurons followed by a mini-stroke impairs spatial learning in rats. Read More »

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