Author name: Kristen Hartman

Interactions between noncholinergic basal forebrain neurons and muscarinic receptors in attentional processing

Kozikowski CT, Wolfe EL, Yanev PG, Burk JA (2014) Interactions between noncholinergic basal forebrain neurons and muscarinic receptors in attentional processing. Neuroscience 2014 Abstracts 263.16. Society for Neuroscience, Washington, DC. Summary: Numerous studies have provided evidence that basal forebrain corticopetal cholinergic neurons are critical for normal attentional performance. However, the role of noncholinergic basal forebrain […]

Interactions between noncholinergic basal forebrain neurons and muscarinic receptors in attentional processing Read More »

Lesions of hindbrain catecholaminergic projections to nucleus accumbens, bed nucleus of the stria terminalis, lateral parabrachial nucleus or locus coeruleus do not impair glucoprivic feeding

Dinh TT, Huston N, Ritter S (2014) Lesions of hindbrain catecholaminergic projections to nucleus accumbens, bed nucleus of the stria terminalis, lateral parabrachial nucleus or locus coeruleus do not impair glucoprivic feeding. Neuroscience 2014 Abstracts 256.05. Society for Neuroscience, Washington, DC. Summary: We have shown previously that injection of the retrogradely transported immunotoxin, anti-dopamine beta-hydroxylase

Lesions of hindbrain catecholaminergic projections to nucleus accumbens, bed nucleus of the stria terminalis, lateral parabrachial nucleus or locus coeruleus do not impair glucoprivic feeding Read More »

Selective ablation of mu opioid receptor expressing gaba neurons in the rostromedial tegmental nucleus promotes ethanol intake

Fu R, Chen X, Zho W, Li J, Ye J-H (2014) Selective ablation of mu opioid receptor expressing gaba neurons in the rostromedial tegmental nucleus promotes ethanol intake. Neuroscience 2014 Abstracts 267.30. Society for Neuroscience, Washington, DC. Summary: BACKGROUND AND PURPOSE The cellular mechanisms underlying the aversive effect of ethanol that limits its intake are

Selective ablation of mu opioid receptor expressing gaba neurons in the rostromedial tegmental nucleus promotes ethanol intake Read More »

Efficient elimination of CD103-expressing cells by anti-CD103 antibody drug conjugates in immunocompetent mice.

Mang Y, Zhao Z, Zeng Z, Wu X, Li Z, Zhang L (2015) Efficient elimination of CD103-expressing cells by anti-CD103 antibody drug conjugates in immunocompetent mice. Int Immunopharmacol 24:119-127. doi: 10.1016/j.intimp.2014.11.004 Summary: Previous work has demonstrated that an M290-SAP custom conjugate promoted the long-term survival of pancreatic islet allografts by reducing the number of CD103+

Efficient elimination of CD103-expressing cells by anti-CD103 antibody drug conjugates in immunocompetent mice. Read More »

Eye-specific retinogeniculate segregation proceeds normally following disruption of patterned spontaneous retinal activity.

Speer C, Sun C, Liets L, Stafford B, Chapman B, Cheng H (2014) Eye-specific retinogeniculate segregation proceeds normally following disruption of patterned spontaneous retinal activity. Neural Dev 9:25. doi: 10.1186/1749-8104-9-25 Summary: The authors administered 0.88-1.66 μg of an Anti-VaChT-SAP custom conjugate to ferrets with an intraocular injection. Although the lesioned animals demonstrated normal eye-specific retinogeniculate

Eye-specific retinogeniculate segregation proceeds normally following disruption of patterned spontaneous retinal activity. Read More »

Cholinergic neurons of the basal forebrain mediate biochemical and electrophysiological mechanisms underlying sleep homeostasis.

Kalinchuk A, Porkka-Heiskanen T, McCarley R, Basheer R (2015) Cholinergic neurons of the basal forebrain mediate biochemical and electrophysiological mechanisms underlying sleep homeostasis. Eur J Neurosci 41:182-195. doi: 10.1111/ejn.12766 Summary: Previous work has indicated that non-rapid eye movement during recovery sleep after sleep deprivation requires cholinergic neurons in the BF. The authors examined how BF

Cholinergic neurons of the basal forebrain mediate biochemical and electrophysiological mechanisms underlying sleep homeostasis. Read More »

Preliminary results from a phase I study of substance P-saporin in terminal cancer patients with intractable pain.

Frankel AE, Nymeyer H, Lappi DA, Higgins D, Ahn C, Noe C (2014) Preliminary results from a phase I study of substance P-saporin in terminal cancer patients with intractable pain. Journal of Clinical Oncology 32:191. doi: 10.1200/jco.2014.32.31_suppl.191 Summary: Existing pain therapies are insufficient to control cancer pain in 10-15% of patients. Substance P (SP) and

Preliminary results from a phase I study of substance P-saporin in terminal cancer patients with intractable pain. Read More »

Role of spinal bombesin-responsive neurons in nonhistaminergic itch.

Akiyama T, Tominaga M, Takamori K, Carstens M, Carstens E (2014) Role of spinal bombesin-responsive neurons in nonhistaminergic itch. J Neurophysiol 112:2283-2289. doi: 10.1152/jn.00409.2014 Summary: Recent papers have demonstrated that pruritogen-evoked scratching behavior is reduced or eliminated by intrathecal injection of Bombesin-SAP (Cat. #IT-40). In this work the authors build on those data by investigating

Role of spinal bombesin-responsive neurons in nonhistaminergic itch. Read More »

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