Author name: Kristen Hartman

Brainstem opioidergic system is involved in early response to experimental SAH.

Cetas J, McFarlane R, Kronfeld K, Smitasin P, Liu J, Raskin J (2015) Brainstem opioidergic system is involved in early response to experimental SAH. Transl Stroke Res 6:140-147. doi: 10.1007/s12975-014-0378-2 Objective: To determine the cause of poor long-term outcomes after Subarachnoid hemorrhage (SAH). Summary: Failure of the RVM μ-opioid receptor cells to initiate the compensatory […]

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SFN Poster of the Year 2014

Congratulations to this year’s winner of ATS’ Poster of the Year featuring IT-42 Anti-ChAT-SAP. Be sure to check out the featured article in Targeting Trends. 692.21 Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in PDK Phillips, A Kucinski, R Albin, M Sarterfeaturing IT-42 Anti-ChAT-SAP (poster; Wednesday, Nov. 19,

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Chronic oxotremorine treatment ameliorates depressive phenotype in a rodent model of Alzheimer’s disease

Nair DV, Al-Badri MM, Peng H, Schenkman N, Pacheco-Quinto J, Eckman CB, Iacono D, Eckman EA (2014) Chronic oxotremorine treatment ameliorates depressive phenotype in a rodent model of Alzheimer’s disease. Neuroscience 2014 Abstracts 670.03. Society for Neuroscience, Washington, DC. Summary: Alzheimer’s disease (AD) is a progressive neurodegenerative condition that is characterized by changes to brain

Chronic oxotremorine treatment ameliorates depressive phenotype in a rodent model of Alzheimer’s disease Read More »

Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in PD.

Phillips K, Kucinski A, Albin R, Sarter M (2014) Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in PD. Neuroscience 2014 Abstracts 692.21. Society for Neuroscience, Washington, DC. Summary: In addition to striatal dopamine loss, degeneration of cholinergic neurons in the basal forebrain (BF) and the brainstem pedunculopontine

Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in PD. Read More »

The role of the basal forebrain cholinergic neurons in cued extinction memory

Schreiber WB, Keller S, Knox D (2014) The role of the basal forebrain cholinergic neurons in cued extinction memory. Neuroscience 2014 Abstracts 748.01. Society for Neuroscience, Washington, DC. Summary: Fear extinction learning and memory requires inhibition of neural activity in amygdala (AMY) nuclei driven by neural substrates in the ventromedial prefrontal cortex (vmPFC), resulting in

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Is selective hippocampal cholinergic deafferentation sufficient to produce temporally graded retrograde amnesia?

Köppen JR, Stuebing SS, Sieg M, Blackwell AA, Blankenship P, Grisley ED, Cheatwood JL, Wallace DG (2014) Is selective hippocampal cholinergic deafferentation sufficient to produce temporally graded retrograde amnesia?. Neuroscience 2014 Abstracts 749.20. Society for Neuroscience, Washington, DC. Summary: Dementia of the Alzheimer’s type (DAT) is a neurodegenerative disorder marked by degeneration of basal forebrain

Is selective hippocampal cholinergic deafferentation sufficient to produce temporally graded retrograde amnesia? Read More »

The galantamine prodrug, Memogain®, reverses deficits in hippocampal neurogenesis associated with the loss of basal forebrain cholinergic neurons

Van Kampen JM, Kay DG, Maelicke A (2014) The galantamine prodrug, Memogain®, reverses deficits in hippocampal neurogenesis associated with the loss of basal forebrain cholinergic neurons. Neuroscience 2014 Abstracts 789.21. Society for Neuroscience, Washington, DC. Summary: Loss of basal forebrain cholinergic innervation of the hippocampus and severe neuronal loss within the hippocampal CA1 region are

The galantamine prodrug, Memogain®, reverses deficits in hippocampal neurogenesis associated with the loss of basal forebrain cholinergic neurons Read More »

The effects of targeted intracerebral saporin injection on recovery from stroke

Becker A, Goldberg M (2014) The effects of targeted intracerebral saporin injection on recovery from stroke. Neuroscience 2014 Abstracts 800.09. Society for Neuroscience, Washington, DC. Summary: It is well known that the diffuse neuromodulatory systems of the brain play a role in cortical plasticity that may extend to cortical reorganization after brain injury. The basal

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Contribution of hindbrain catecholamine neurons to orexin-induced feeding

Li A-J, Wang Q, Davis H, Ritter S (2014) Contribution of hindbrain catecholamine neurons to orexin-induced feeding. Neuroscience 2014 Abstracts 834.08. Society for Neuroscience, Washington, DC. Summary: Both lateral hypothalamic orexinergic neurons and hindbrain catecholaminergic neurons contribute to feeding behavior. In addition, both phenotypes are widely distributed in the brain and their terminal sites are

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Medullary catecholaminergic (CA) neurons modulate hypoxic ventilatory response in neonatal rats (P7-8)

Patrone LA, Biancardi V, Bicego KC, Gargaglioni LH (2014) Medullary catecholaminergic (CA) neurons modulate hypoxic ventilatory response in neonatal rats (P7-8). Neuroscience 2014 Abstracts 643.10. Society for Neuroscience, Washington, DC. Summary: It is known that catecholaminergic (CA) neurons are involved in autonomic and respiratory regulation during low O2 conditions in adult mammals. We evaluated the

Medullary catecholaminergic (CA) neurons modulate hypoxic ventilatory response in neonatal rats (P7-8) Read More »

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